Genetic Code and Regulation problems
- 1. Which of the following techniques was carried out by Nirenberg and Matthaei in 1961 to determine the first codon?
Options- A. In vitro synthesis of a polypeptide using UUUUU
- B. Labeled peptide binding to a ribosome
- C. Mixed co-polymer mRNA synthesis
- D. none of the above Discuss
Correct Answer: In vitro synthesis of a polypeptide using UUUUU
- 2. How many amino acids will be encoded by 5' GAU GGU UGA UGU 3' sequence?
Options- A. One
- B. Two
- C. Three
- D. Four Discuss
Correct Answer: Two
- 3. How many different codons are possible?
Options- A. 3
- B. 20
- C. 64
- D. An infinite number Discuss
Correct Answer: 64
- 4. Codon that specify the amino acids often differs in the
Options- A. first base
- B. second base
- C. third base
- D. none of these Discuss
Correct Answer: third base
- 5. Crick demonstrated that the genetic code involved three bases and suggested that the code was degenerated. What experimental technique Crick conducted to suggest genetic code degeneration?
Options- A. Gel electrophoresis
- B. Density gradient centrifugation
- C. Frameshift mutagenesis
- D. Restriction digests of the rII gene Discuss
Correct Answer: Frameshift mutagenesis
- 6. The genetic code is
Options- A. universal
- B. universal except for rare exceptions in mitochondria and some protozoa
- C. species-specific
- D. kingdom-specific Discuss
Correct Answer: universal except for rare exceptions in mitochondria and some protozoa
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