DNA Structure and Replication problems
- 1. Messelsen and Stahl model of replication was called
Options- A. conservative replication
- B. semi-conservative replication
- C. dispersive replication
- D. Cri du Chat Discuss
Correct Answer: semi-conservative replication
- 2. Enzymes, responsible for unraveling short segments of DNA is
Options- A. DNA polymerase
- B. helicase
- C. DNA ligase
- D. primase Discuss
Correct Answer: helicase
- 3. In the study of one experiment it was found that the value of Tm for DNA is = 40° C. If the cell has 20% GC at the above Tm, then what will be value of 'Tm' if the GC% increases to 60%?
Options- A. Remains same
- B. Increases
- C. Decreases
- D. Can not be compared Discuss
Correct Answer: Increases
- 4. The higher order structure of DNA shows symmetry, whereas the higher order structures of most proteins do not. Why isn't protein shape more regular like DNA?
Options- A. DNA has one main function in cells whereas proteins have many.
- B. The many different amino acid R groups on proteins confer many different shapes.
- C. Some S amino acids cause proteins to bend; others cause protein to flatten.
- D. All of the above Discuss
Correct Answer: All of the above
- 5. The 5' and 3' numbers are related to the
Options- A. length of the DNA strand
- B. carbon number in sugar
- C. the number of phosphates
- D. the base pair rule Discuss
Correct Answer: carbon number in sugar
- 6. Which of the following enzyme adds complementary bases during replication?
Options- A. Helicase
- B. Synthesase
- C. Replicase
- D. Polymerase Discuss
Correct Answer: Polymerase
- 7. In DNA double helix, the two DNA chains are held together by
Options- A. covalent bonds between the pair of bases
- B. hydrogen bonds between the pair of bases
- C. ionic bonds between the pair of bases
- D. none of the above Discuss
Correct Answer: hydrogen bonds between the pair of bases
- 8. The chromosomal DNA complexes with
Options- A. three types of histone as H1, H2A and H4
- B. five types of histone as H1, H2A, H2B, H3 and H4
- C. four types of histone as H1, H2A, H3 and H4
- D. two types of histone as H1 and H4 Discuss
Correct Answer: five types of histone as H1, H2A, H2B, H3 and H4
- 9. Proteins involved in opening a replication bubble are
Options- A. DNA helicases
- B. single stranded binding proteins
- C. ligase
- D. DNA topoisomerase Discuss
Correct Answer: DNA topoisomerase
- 10. When DNA polymerase is in contact with guanine in the parental strand, what does it add to the growing daughter strand?
Options- A. Phosphate
- B. Cytosine
- C. Uracil
- D. Guanine Discuss
Correct Answer: Cytosine
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