Structure and Properties of Peptides problems
- 1. Hemoglobin has quaternary structure and is made up of
Options- A. six polypeptide chains, two ?-chains and four ?-chains
- B. two polypeptide chains, one ?-chains and one ?-chains
- C. four polypeptide chains, two ?-chains and two ?-chains
- D. five polypeptide chains, two ?-chains and three ?-chains Discuss
Correct Answer: four polypeptide chains, two ?-chains and two ?-chains
- 2. What was the first protein whose complete tertiary structure was determined?
Options- A. Lysozyme
- B. Myoglobin
- C. Pancreatic ribonuclease
- D. Pancreatic DNase Discuss
Correct Answer: Myoglobin
- 3. When pO2 = Kd of myoglobin, the fractional saturation (YO2) is about
Options- A. 0.1
- B. 0.5
- C. 0.9
- D. 1.7 Discuss
Correct Answer: 0.5
- 4. Which of the following is an example of tertiary structure in a protein?
Options- A. A multimeric protein
- B. An a-helix
- C. A P-pleated sheet
- D. A globular domain Discuss
Correct Answer: A globular domain
- 5. The oxygen binding curves of hemoglobin and myoglobin
Options- A. allow maximum transfer of oxygen to the tissues
- B. are a consequence of the quaternary structure of hemoglobin
- C. both (a) and (b)
- D. are identical Discuss
Correct Answer: both (a) and (b)
- 6. Which of the following statements is incorrect?
Options- A. Protein G contains both a-helix and P-sheet
- B. Protein G contains only a-helix
- C. Fatty acid binding protein contains largely P-sheet
- D. Hemoglobin contains four sub-units Discuss
Correct Answer: Protein G contains only a-helix
- 7. In the ?-pleated sheet
Options- A. hydrogen bonds are formed between the peptide bonds
- B. adjacent polypeptide chains can either be parallel or antiparallel
- C. the polypeptide chain is fully extended
- D. all of the above Discuss
Correct Answer: all of the above
- 8. In ?-pleated sheet structures neighbouring
Options- A. chains lie in a flat plane
- B. neighboring residues are hydrogen bonded
- C. neighboring chains are connected by a-helices
- D. neighboring chains are hydrogen bonded Discuss
Correct Answer: neighboring chains are hydrogen bonded
- 9. The same peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala. was digested with chymotrypsin to produce
Options- A. Val-Lys + Glu-Met-Ser + Trp-Arg-Ala.
- B. Val-Lys-Glu-Met-Ser-Trp + Arg-Ala.
- C. Val-Lys-Glu-Met-Ser + Trp-Arg-Ala.
- D. Val-Lys-Glu-Met + Ser-Trp-Arg-Ala. Discuss
Correct Answer: Val-Lys-Glu-Met-Ser-Trp + Arg-Ala.
- 10. Which of the following statement is incorrect?
Options- A. Hemoglobin and myoglobin are the two oxygen binding proteins
- B. Hemoglobin transports O2 in the blood
- C. Myoglobin stores O2 in muscles
- D. None of the above Discuss
Correct Answer: None of the above
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