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Home Biochemistry Genetic Code and Regulation Comments

  • Question
  • Crick demonstrated that the genetic code involved three bases and suggested that the code was degenerated. What experimental technique Crick conducted to suggest genetic code degeneration?


  • Options
  • A. Gel electrophoresis
  • B. Density gradient centrifugation
  • C. Frameshift mutagenesis
  • D. Restriction digests of the rII gene

  • Correct Answer
  • Frameshift mutagenesis 


  • Genetic Code and Regulation problems


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    • 1. Codon that specify the amino acids often differs in the

    • Options
    • A. first base
    • B. second base
    • C. third base
    • D. none of these
    • Discuss
    • 2. How many different codons are possible?

    • Options
    • A. 3
    • B. 20
    • C. 64
    • D. An infinite number
    • Discuss
    • 3. How many amino acids will be encoded by 5' GAU GGU UGA UGU 3' sequence?

    • Options
    • A. One
    • B. Two
    • C. Three
    • D. Four
    • Discuss
    • 4. Which of the following techniques was carried out by Nirenberg and Matthaei in 1961 to determine the first codon?

    • Options
    • A. In vitro synthesis of a polypeptide using UUUUU
    • B. Labeled peptide binding to a ribosome
    • C. Mixed co-polymer mRNA synthesis
    • D. none of the above
    • Discuss
    • 5. In some organelles in eukaryotes, the genetic code for some codons

    • Options
    • A. differs from that used in prokaryotes
    • B. are same
    • C. are partially same
    • D. none of the above
    • Discuss
    • 6. The genetic code is

    • Options
    • A. universal
    • B. universal except for rare exceptions in mitochondria and some protozoa
    • C. species-specific
    • D. kingdom-specific
    • Discuss
    • 7. Upstream regions which are essential for correct transcription are called

    • Options
    • A. enhancers
    • B. start codons
    • C. promoters
    • D. transcription factors
    • Discuss
    • 8. Immediately after transcription

    • Options
    • A. a methylated guanine cap is added to the 51 end of the transcript
    • B. a methylated guanine cap is added to the 31 end of the transcript
    • C. both (a) and (b)
    • D. a poly adenylation signal is added
    • Discuss
    • 9. RNA polymerase in prokaryotes has a removable

    • Options
    • A. alpha subunit
    • B. beta subunit
    • C. both (a) and (b)
    • D. sigma subunit
    • Discuss
    • 10. Transcription factors are

    • Options
    • A. promoters
    • B. proteins which bind to DNA and regulate transcription
    • C. TATA boxes
    • D. CATT boxes
    • Discuss


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