Disease Associated with Immune System problems
- 1. If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced
Options- A. alternative complement activation.
- B. CD8 T cell-mediated cytotoxicity
- C. macrophage activation to vesicular pathogens
- D. IgG synthesis Discuss
Correct Answer: alternative complement activation.
- 2. The HIV virus infects primarily
Options- A. brain cells
- B. cells in the immune system
- C. red blood cells
- D. liver cells Discuss
Correct Answer: cells in the immune system
- 3. A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind
Options- A. Leu or Ileu
- B. His or Pro
- C. Tyr or Phe
- D. Ser or Thr Discuss
Correct Answer: Tyr or Phe
- 4. The primary reason for AIDS, a deadly disease is that it
Options- A. is caused by a virus
- B. is caused by a bacterium
- C. destroys key components of the body's internal defense system
- D. causes a breakdown of the body's inflammatory response Discuss
Correct Answer: destroys key components of the body's internal defense system
- 5. The chemical, typically released by the body in an allergic response is
Options- A. histamine
- B. allergens
- C. antihistamines
- D. perforins Discuss
Correct Answer: histamine
- 6. An example of an immunodeficiency disorder is
Options- A. thyroiditis
- B. rheumatic fever
- C. systemic lupus erythematosus
- D. AIDS Discuss
Correct Answer: AIDS
- 7. To treat HIV infections using drugs, the major problem is that
Options- A. the drugs that are good inhibitors cannot by synthesized
- B. the drugs interfere with normal digestion
- C. the virus particles with altered (mutant) proteases arise
- D. the drugs are rapidly degraded Discuss
Correct Answer: the virus particles with altered (mutant) proteases arise
- 8. A selective IgA deficiency would be expected to result in problems with
Options- A. bacterial infections
- B. infections following dental work due to bacteria entering the bloodstream
- C. mucosal pathogens
- D. pathogens which can survive inside macrophages Discuss
Correct Answer: mucosal pathogens
- 9. Bone marrow given to an infant with SCID must
Options- A. be irradiated to eliminate GVHD
- B. contain mature T cells that can begin making immune responses immediately
- C. come from a donor that shares some MHC alleles with the recipient
- D. come from one of the child's parents Discuss
Correct Answer: come from a donor that shares some MHC alleles with the recipient
- 10. Combined cellular and humoral immune deficiencies result from lack of all of the following except
Options- A. a thymus
- B. class II MHC
- C. HIV infection of CD4+ T cells
- D. transporter of antigen peptides (TAP) Discuss
Correct Answer: transporter of antigen peptides (TAP)
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