Glycolysis problems
- 1. During glycolysis, the major energy generating step involves
Options- A. pyruvate kinase
- B. phosphoglycerate kinase
- C. glyceraldehyde-3 -dehydrogenase
- D. Phosphofructokinase Discuss
Correct Answer: glyceraldehyde-3 -dehydrogenase
- 2. ATP is from which general category of molecules?
Options- A. Polysaccharides
- B. Proteins
- C. Nucleotides
- D. Amino acids Discuss
Correct Answer: Nucleotides
- 3. Which of the following is not a mechanism for altering the flux of metabolites through the rate-determining step of a pathway?
Options- A. Allosteric control of the enzyme activity
- B. Diffusional coupling between adjacent active sites
- C. Genetic control of the enzyme concentration
- D. Covalent modification of the enzyme Discuss
Correct Answer: Diffusional coupling between adjacent active sites
- 4. Glycolytic pathway regulation involves
Options- A. allosteric stimulation by ADP
- B. allosteric inhibition by ATP
- C. feedback, or product, inhibition by ATP
- D. all of the above Discuss
Correct Answer: all of the above
- 5. In the glycogen synthase reaction, the precursor to glycogen is
Options- A. glucose-6-P
- B. UTP-glucose
- C. UDP-glucose
- D. glucose-1-P Discuss
Correct Answer: UDP-glucose
- 6. Glucose from the breakdown of glycogen is obtained in
Options- A. the liver by phosphorolysis
- B. the muscles by phosphorolysis
- C. the muscles by hydrolysis
- D. both (a) and (b) Discuss
Correct Answer: both (a) and (b)
- 7. Glycogen has
Options- A. ?-1,4 linkage
- B. ?-1,6 linkages
- C. ?-1,4 and ?-1,6 linkages
- D. ?-1,4 and ?-1,6 linkage Discuss
Correct Answer: ?-1,4 and ?-1,6 linkages
- 8. The released energy obtained by oxidation of glucose is stored as
Options- A. a concentration gradient across a membrane
- B. ADP
- C. ATP
- D. NAD+ Discuss
Correct Answer: ATP
- 9. In glycolysis, ATP is formed by the transfer of a high-energy phosphate from 1,3-bisphosphoglycerate to ADR No such high-energy phosphate donor has ever been isolated in mitochondria because
Options- A. the techniques for isolating the phosphate donor are not refined enough
- B. no such phosphate donor exists
- C. the high-energy phosphate donor is very short-lived and difficult to isolate
- D. None of the above Discuss
Correct Answer: no such phosphate donor exists
- 10. Phosphofructokinase, the major flux-controlling enzyme of glycolysis is allosterically inhibited and activated respectively by
Options- A. ATP and PEP
- B. AMP and Pi
- C. ATP and ADP
- D. Citrate and ATP Discuss
Correct Answer: ATP and ADP
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