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Nucleic Acids (Biochemistry) Question and Answers-Page first

Nucleic Acids problems


  • 1. The glycosidic bonds in DNA and RNA

  • Options
  • A. connect the sugar to the base
  • B. can be hydrolyzed by OH- ion
  • C. stabilize Watson-Crick H-bonds
  • D. are free to rotate over about 180°
  • Discuss
  • 2. Thymidine

  • Options
  • A. can participate in hydrophobic interactions due to its methyl group
  • B. is replaced by uracil in RNA
  • C. normally forms two hydrogen bonds with adenosine
  • D. all of the above
  • Discuss
  • 3. In gel electrophoresis, what fragments will move most quickly through a gel?

  • Options
  • A. Large fragments
  • B. Small fragments
  • C. Large genome
  • D. None of these
  • Discuss
  • 4. A purine with an amine (NH2) group on the 6th carbon is

  • Options
  • A. adenine
  • B. cytosine
  • C. thymine
  • D. guanine
  • Discuss
  • 5. Because DNA is a highly charged polyanion, its stability to heat denaturation

  • Options
  • A. does not depend on hydrophobic interactions
  • B. increases with increasing salt
  • C. is independent of G - C content
  • D. decreases with increasing salt
  • Discuss
  • 6. The unfavourable free energy associated with not satisfying a hydrogen bond after formation of the double helix is approximately

  • Options
  • A. 10 kJ/mol
  • B. 20 kJ/mol
  • C. 25 kJ/mol
  • D. 30 kJ/mol
  • Discuss
  • 7. Nucleotide bases and aromatic amino acids absorb light respectively at

  • Options
  • A. 280 and 260 nm
  • B. 260 and 280 nm
  • C. 270 and 280 nm
  • D. 260 and 270 nm
  • Discuss
  • 8. A nucleotide consists of

  • Options
  • A. a sugar, a base and a phosphate
  • B. a sugar and a phosphate
  • C. paired bases
  • D. a sugar, a base and three phosphates
  • Discuss
  • 9. Which of the following is a purine?

  • Options
  • A. Cytosine
  • B. Adenine
  • C. Thymine
  • D. Uracil
  • Discuss
  • 10. A five carbon sugar lacking a hydrogen at the number 2 carbon is found in

  • Options
  • A. DNA
  • B. RNA
  • C. mRNA
  • D. rDNA
  • Discuss

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