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DNA Structure and Replication problems


  • 1. In DNA, nucleotides are covalently joined together by

  • Options
  • A. 3', 5' phosphodiester bonds to form a repetitive sugar-phosphate chain
  • B. 2', 5' phosphodiester bonds to form a repetitive sugar-phosphate chain
  • C. 2', 3' phosphodiester bonds to form a repetitive sugar-phosphate chain
  • D. 3', 4' phosphodiester bonds to form a repetitive sugar-phosphate chain
  • Discuss
  • 2. TM refers to the temperature at which

  • Options
  • A. membranes are 50% fluid
  • B. 50% of a DNA molecule is denatured
  • C. 50% of a protein molecules are denatured
  • D. all of the above
  • Discuss
  • 3. Which polymerase is active in DNA repairing

  • Options
  • A. Polymerase I
  • B. Polymerase II
  • C. Polymerase III
  • D. none of these
  • Discuss
  • 4. Proteins which help to open the double helix for DNA synthesis are

  • Options
  • A. DNA helicases
  • B. single stranded binding proteins
  • C. ligase
  • D. DNA topoisomerase
  • Discuss
  • 5. The site on a bacterial chromosome that marks the initiation point for chromosome replication is called

  • Options
  • A. Ori
  • B. a promoter
  • C. Pro
  • D. an initiation codon
  • Discuss
  • 6. What is the exact name of the classical Watson-Crick double helix DNA?

  • Options
  • A. A-DNA
  • B. B-DNA
  • C. Z-DNA
  • D. X-DNA
  • Discuss
  • 7. First evident that DNA is genetic material comes from the experiment of Griffith is

  • Options
  • A. transduction
  • B. transformation
  • C. replication
  • D. translation
  • Discuss
  • 8. Which of the following is not a structural motif in DNA binding proteins?

  • Options
  • A. bZIP
  • B. helix-turn-helix
  • C. TFIID
  • D. zinc finger
  • Discuss
  • 9. An RNA primer is synthesized by

  • Options
  • A. DNA helicases
  • B. ligase
  • C. DNA topoisomerase
  • D. primase
  • Discuss
  • 10. What is the name given to the points at which a DNA helix is unwound and new strands develop?

  • Options
  • A. Replication origins
  • B. Replication forks
  • C. Leading strands
  • D. Okazaki fragments
  • Discuss

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