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DNA Structure and Replication problems


  • 1. The DNA is negatively super coiled, complexes to histone,

  • Options
  • A. HU
  • B. HSP-1
  • C. H-NS
  • D. All of these
  • Discuss
  • 2. An important difference between eukaryotic and prokaryotic DNA replication is

  • Options
  • A. eukaryotic DNA polymerases are faster
  • B. more DNA polymerases are found in eukaryotes
  • C. multiple origins of replication in eukaryotes
  • D. RNA primers are not required in eukaryotes
  • Discuss
  • 3. What does ligase do during replication of DNA?

  • Options
  • A. Synthesizes the lagging strand
  • B. Makes copies of mRNA from DNA
  • C. Joins nicks in DNA strands
  • D. Digests mRNA when it is no longer needed
  • Discuss
  • 4. Which will require a higher temperature to denature?

  • Options
  • A. DNA with a high G-C content
  • B. DNA with a high A-T content
  • C. RNA with a high G-C content
  • D. RNA with a high A-T content
  • Discuss
  • 5. For the DNA replication in eukaryotes, the cell cycle consists of

  • Options
  • A. G1, G2 and M phases
  • B. S, G2 and M phases
  • C. G1,S, G2 and M phases
  • D. G2 and M phases
  • Discuss
  • 6. DNA segments capable of moving from one place in the genome to another is known as

  • Options
  • A. transposons
  • B. retrovirus
  • C. introns
  • D. moving elements
  • Discuss
  • 7. DNA with a G-C content of 50% will melt at approximately

  • Options
  • A. 60°C
  • B. 70 °C
  • C. 90 °C
  • D. 100 °C
  • Discuss
  • 8. DNA replication in eukaryotes occurs only in

  • Options
  • A. G1 phase
  • B. S phase
  • C. G2 phase
  • D. M phase
  • Discuss
  • 9. Who's X-ray work aided Watson and Crick in their discovery of the double helix?

  • Options
  • A. W.H. Bragg
  • B. R. Franklin
  • C. L. Pauling
  • D. Leaderberg
  • Discuss
  • 10. The B-DNA structure found in solution is a

  • Options
  • A. left-handed double helix of antiparallel chains (10 bp/turn)
  • B. right-handed double helix of antiparallel chains (?10 bp/turn)
  • C. left-handed zig-zag helix of antiparallel chains (10 bp/turn)
  • D. right-handed double helix of parallel chains (?10 bp/turn)
  • Discuss

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