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- Question
The binding of ligands to many G-proteins linked receptors leads to shortlived
Options- A. increase in the concentration of certain intracellular signaling molecules called second messenger
- B. decrease in the concentration of certain intracellular signaling molecules called second messenger
- C. increase in the concentration of certain extracellular signaling molecules called first messenger
- D. decrease in the concentration of certain extracellular signaling molecules called first messenger
- Correct Answer
- increase in the concentration of certain intracellular signaling molecules called second messenger
- 1. Simple nerve reflexes use signaling molecules called
Options- A. neurotransmitters
- B. nitric oxides
- C. G proteins
- D. proteases Discuss
- 2. The major second messengers are
Options- A. cAMP
- B. cGMP
- C. DAG
- D. All of these Discuss
- 3. Cell signaling can be classified into
Options- A. three distinct types based on the distance over which the signaling molecules act
- B. two distinct types based on the distance over which the signaling molecules act
- C. three distinct types based on the signaling molecules
- D. none of the above Discuss
- 4. The hormone or ligand can be considered as
Options- A. first messenger
- B. second messenger
- C. both (a) and (b)
- D. none of these Discuss
- 5. Which of the following is a second messenger?
Options- A. lnositol 1,4,5-triphosphate
- B. Diacyl glycerol
- C. Phospholipase C
- D. Both (a) and (b) Discuss
- 6. The enzyme that catalyzes the splitting of PIP2 into two molecules of inositol triphosphate (IP3) and diacylglycerol in cell signaling, is
Options- A. phosphokinase C
- B. phospholipase C
- C. phosphodiesterase C
- D. lipokinase Discuss
- 7. Which of the following statement is incorrect?
Options- A. The principal lipophilic hormones that binds to receptors located in the plasma membranes are prostaglandins
- B. Prostaglandins are synthesized from arachidonic acid
- C. Prostaglandins act as paracrine signaling molecules
- D. None of the above Discuss
- 8. In paracrine signaling, the signaling molecules affects only
Options- A. target cells close to the cell from which it was secreted
- B. target cells distant from its site of synthesis in cells of an endocrine organ
- C. both (a) and (b)
- D. none of the above Discuss
- 9. A signal cascade induced by adrenaline or thyroxine
Options- A. must begin with receipt of the signal molecule by a surface receptor
- B. involves the activation of a G protein
- C. results in the activation of a sequence of enzymes needed for the cell effect
- D. all of the above Discuss
- 10. Self-phosphorylation is an excellent mechanism for triggering specific catalytic function of the proteins involved in signal cascades because it
Options- A. changes the shape and thus the enzymatic activity of the proteins involved
- B. makes the receptor more likely to capture the signaling, molecule
- C. allows hydrophilic signaling molecules to cross the plasma membrane
- D. None of the above Discuss
Cell Signalling and Transduction problems
Search Results
Correct Answer: neurotransmitters
Correct Answer: All of these
Correct Answer: three distinct types based on the distance over which the signaling molecules act
Correct Answer: first messenger
Correct Answer: Both (a) and (b)
Correct Answer: phospholipase C
Correct Answer: None of the above
Correct Answer: target cells close to the cell from which it was secreted
Correct Answer: all of the above
Correct Answer: changes the shape and thus the enzymatic activity of the proteins involved
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