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Genetic Regulation Prokaryotes problems


  • 1. Catabolite activating protein exerts __________ control on transcription of the lac operon genes.

  • Options
  • A. positive
  • B. negative
  • C. may be positive or negative
  • D. none of these
  • Discuss
  • 2. Genes which need to be coordinately regulated but are not in operons may be regulated by

  • Options
  • A. common transcription factor binding domains
  • B. TATA boxes
  • C. CAAT regions
  • D. GC regions
  • Discuss
  • 3. The lac operon is transcribed in which segments?

  • Options
  • A. 1
  • B. 2
  • C. 3
  • D. 4
  • Discuss
  • 4. Which of the following occur in the presence of glucose?

  • Options
  • A. lac Z gene expression is increased
  • B. cAMP increases
  • C. Binding of CAP-cAMP complex to the promoter area decreases
  • D. none of the above
  • Discuss
  • 5. DNA is methylated at

  • Options
  • A. AC sequences
  • B. TATA sequences
  • C. CAAT sequences
  • D. CG sequences
  • Discuss
  • 6. A frameshift mutation occurs in the sigma subunit gene transcribed as part of SPOl early genes. What will be the immediate result?

  • Options
  • A. Early genes will not be translated
  • B. Middle genes will not be transcribed
  • C. The bacterial host will lyse immediately
  • D. Infection will proceed as usual
  • Discuss
  • 7. In the presence of high levels of tryptophan

  • Options
  • A. attenuator allows transcription of trp structural genes
  • B. attenuator propogates transcription
  • C. attenuator terminates transcription
  • D. none of the above
  • Discuss
  • 8. Which of the following is not a transcription factor?

  • Options
  • A. Helix-turn-helix proteins
  • B. Zinc finger proteins
  • C. Leucine zipper proteins
  • D. Steroid hormones
  • Discuss
  • 9. Tubulin is regulated by

  • Options
  • A. binding of tubulin to tubulin mRNA
  • B. splicing of the tubulin transcript
  • C. binding of tubulin to the tubulin translational product
  • D. binding of tubulin to DNA
  • Discuss
  • 10. Enhancers differ from promoters in that

  • Options
  • A. they initiate transcription
  • B. they are adjacent to the start codon
  • C. their orientation can be inverted without effect
  • D. they are restricted to a specific gene
  • Discuss

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