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Home Biochemistry DNA Structure and Replication Comments

  • Question
  • Each replication bubbles consists of


  • Options
  • A. 3 replication forks
  • B. 2 replication forks
  • C. 4 replication forks
  • D. 1 replication forks

  • Correct Answer
  • 2 replication forks 


  • DNA Structure and Replication problems


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    • 1. The packing ratio of nucleosomes is about

    • Options
    • A. 6
    • B. 8
    • C. 7
    • D. 9
    • Discuss
    • 2. The enzyme responsible for breaking the hydrogen bonds, and thus separating the DNA strands during DNA synthesis is

    • Options
    • A. DNA polymerase
    • B. strandase
    • C. helicase
    • D. none of these
    • Discuss
    • 3. Which of the following species lack a 'classical' histone H1?

    • Options
    • A. Saccharomyces cerevisiae
    • B. Strongylocentrotus purpuratus
    • C. Xenopus laevis
    • D. Arabidopsis thaliana
    • Discuss
    • 4. The replication of a linear DNA molecule in a eukaryotic chromosome creates a problem which is reported to be sorted out by

    • Options
    • A. using enzyme called telomerase
    • B. shortening of the double stranded replicated portion
    • C. using RNA as a template
    • D. none of the above
    • Discuss
    • 5. The role of primase is to

    • Options
    • A. dismantle RNA primer
    • B. cleave and unwinds short sections of DNA ahead of the replication fork
    • C. proofread base pairing
    • D. synthesize an RNA primer to begin the elongation process
    • Discuss
    • 6. The nicks or gaps between Okazaki fragments are eventually sealed by

    • Options
    • A. gyrase
    • B. DNA ligase
    • C. RNA ligase
    • D. polymerase
    • Discuss
    • 7. The rapid appearance of HIV-1 strains that are resistant to AIDS drugs is due in part to which of the following property of its reverse transcriptase?

    • Options
    • A. AZT (zidovudine) is too expensive to be taken in effective doses
    • B. The RNase H domain of p66 causes error prone synthesis
    • C. It lacks a proofreading exonuclease
    • D. It has low affinity for the correct dNTP's
    • Discuss
    • 8. 30 nm wide helix with five or six nucleosomes per helix is known as

    • Options
    • A. solenoid
    • B. halonoid
    • C. kinoplast
    • D. none of these
    • Discuss
    • 9. What is the approximate percentage of repetitive DNA sequences in human DNA?

    • Options
    • A. 10 to 20%
    • B. 20 to 30%
    • C. 30 to 40%
    • D. 40 to 50%
    • Discuss
    • 10. Okazaki fragments occur on the __________ and are bonded together by __________

    • Options
    • A. Leading strand, polymerase
    • B. mRNA, anticodons
    • C. Lagging strand, ligase
    • D. tRNA, polymerase
    • Discuss


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