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Home Biochemistry Gas Chromatography Comments

  • Question
  • Which of the following is not used for detection in GC?


  • Options
  • A. Infrared spectroscopy
  • B. NMR
  • C. Flame ionisation
  • D. Electrical conductivity

  • Correct Answer
  • NMR 


  • Gas Chromatography problems


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    • 1. Which of the following detectors give mass flow-dependent signals?

    • Options
    • A. Electron capture detector
    • B. Field ionisation detector
    • C. Thermal conductivity detector
    • D. All of the above
    • Discuss
    • 2. The column is heated to

    • Options
    • A. prevent analyte condensation within the column
    • B. control elution of the different analytes
    • C. reduce band broadening to get sharper peaks
    • D. all of these
    • Discuss
    • 3. Resolution is proportional to the

    • Options
    • A. number of theoretical plates in a column
    • B. square root of the number of theoretical plates in a column
    • C. square of the number of theoretical plates in a column
    • D. cube root of the number of theoretical plates in a column
    • Discuss
    • 4. In column switching chromatography

    • Options
    • A. compounds trapped on one column are eluted to another column
    • B. one column is removed and replaced by another
    • C. the flow to the column is switched on and off repeatedly
    • D. any of the above
    • Discuss
    • 5. Derivatisation of a sample is carried out to

    • Options
    • A. reduce polarity of the analytes
    • B. increase the detector response
    • C. increase volatility of the analytes
    • D. all of the above
    • Discuss
    • 6. Which of these effects result from slow injection of a large sample volume?

    • Options
    • A. Increased resolution
    • B. Decreased resolution
    • C. Non-linear detector response
    • D. Constant resolution
    • Discuss
    • 7. Column bleeding occurs when

    • Options
    • A. elution of the analyte is extended over time
    • B. the column is cracked and stationary phase leaks out
    • C. traces of the stationary phase are eluted
    • D. the column breaks during installation and causes personal injury
    • Discuss
    • 8. What does the selectivity factor describe?

    • Options
    • A. The proportional difference in widths of two chromatographic peaks
    • B. The maximum number of different species which a column can separate simultaneously
    • C. The relative separation achieved between two species
    • D. None of the above
    • Discuss
    • 9. Helium is generally preferred as carrier gas over nitrogen and hydrogen because

    • Options
    • A. it is inert
    • B. it has a lower viscosity
    • C. it doubles up as a party gas for balloons and funny voices
    • D. all of above
    • Discuss
    • 10. Doubling the column's length increases resolution by a factor of

    • Options
    • A. (2)0.5
    • B. 2
    • C. 3
    • D. 4
    • Discuss


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