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  • Question
  • Which of the following (s) is/are serine proteases?


  • Options
  • A. Chymotrypsin
  • B. Trypsin
  • C. Elastase
  • D. all of these

  • Correct Answer
  • all of these 


  • Enzymes problems


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    • 1. The cleavage specificity of trypsin and chymotrypsin depend in part on the

    • Options
    • A. proximity of Ser 195 to the active site or specificity pocket
    • B. size, shape, and charge of the active site or specificity pocket
    • C. presence of a low-barrier hydrogen bond in the active site or specificity pocket
    • D. absence of water in the active site
    • Discuss
    • 2. The E.coli pyruvic acid dehydrogenase complex is reported to

    • Options
    • A. decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2
    • B. Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2
    • C. retard the reduction of pyruvic acid to acetyl Co A and CO2
    • D. Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
    • Discuss
    • 3. The role of Asp 102 and His 57 during trypsin catalysis is to

    • Options
    • A. neutralize the charge on the other's side chain
    • B. keep the specificity pocket open
    • C. function as a proton shuttle
    • D. clamp the substrate into the active site
    • Discuss
    • 4. Which of the common features are shared between serine and aspartate proteases?

    • Options
    • A. Both require water to complete the catalytic cycle
    • B. Both use a base to activate the nucleophile
    • C. Both show specificity for certain amino acid sequences
    • D. All of the above
    • Discuss
    • 5. How is the enzyme COX-1 important in human health?

    • Options
    • A. It helps to transport carbon dioxide in the blood
    • B. It is critical for the biosynthesis of DNA
    • C. It is a chemical derivative of aspirin
    • D. It catalyzes the production of hormones that maintain the stomach lining
    • Discuss
    • 6. Which of the following is incorrect with regard to antigen epitopes?

    • Options
    • A. An epitope may be shared by two different antigens
    • B. A protein molecule usually contains multiple epitopes
    • C. B cells bind only processed antigen epitopes
    • D. Epitopes may be linear or assembled
    • Discuss
    • 7. Very low doses of antigen may induce

    • Options
    • A. hypersensitivity
    • B. immunological ignorance
    • C. low zone tolerance
    • D. low zone immunity
    • Discuss
    • 8. CD antigens

    • Options
    • A. allow leukocytes to recognize antigen
    • B. are each expressed on only one cell type
    • C. are expressed on immune cells to mark them for separation
    • D. function as receptors for cytokine and CAMs
    • Discuss
    • 9. A molecule that can be covalently linked to a non-immunogenic antigen to make it an immunogen is called a (n)

    • Options
    • A. adjuvant
    • B. carrier
    • C. hapten
    • D. mitogen
    • Discuss
    • 10. The ability of an antigen to induce an immune response does not depend on the antigen's

    • Options
    • A. ability to enter the thyroid
    • B. degree of aggregation
    • C. dose
    • D. size
    • Discuss


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