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Home Biochemistry Glycolysis Comments

  • Question
  • Phosphofructokinase, the major flux-controlling enzyme of glycolysis is allosterically inhibited and activated respectively by


  • Options
  • A. ATP and PEP
  • B. AMP and Pi
  • C. ATP and ADP
  • D. Citrate and ATP

  • Correct Answer
  • ATP and ADP 


  • Glycolysis problems


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    • 1. In glycolysis, ATP is formed by the transfer of a high-energy phosphate from 1,3-bisphosphoglycerate to ADR No such high-energy phosphate donor has ever been isolated in mitochondria because

    • Options
    • A. the techniques for isolating the phosphate donor are not refined enough
    • B. no such phosphate donor exists
    • C. the high-energy phosphate donor is very short-lived and difficult to isolate
    • D. None of the above
    • Discuss
    • 2. The released energy obtained by oxidation of glucose is stored as

    • Options
    • A. a concentration gradient across a membrane
    • B. ADP
    • C. ATP
    • D. NAD+
    • Discuss
    • 3. Glycogen has

    • Options
    • A. ?-1,4 linkage
    • B. ?-1,6 linkages
    • C. ?-1,4 and ?-1,6 linkages
    • D. ?-1,4 and ?-1,6 linkage
    • Discuss
    • 4. Glucose from the breakdown of glycogen is obtained in

    • Options
    • A. the liver by phosphorolysis
    • B. the muscles by phosphorolysis
    • C. the muscles by hydrolysis
    • D. both (a) and (b)
    • Discuss
    • 5. In the glycogen synthase reaction, the precursor to glycogen is

    • Options
    • A. glucose-6-P
    • B. UTP-glucose
    • C. UDP-glucose
    • D. glucose-1-P
    • Discuss
    • 6. Which of the following regulates glycolysis steps?

    • Options
    • A. Phosphofructokinase
    • B. Hexose kinase
    • C. Pyruvate kinase
    • D. All of these
    • Discuss
    • 7. Which of the following is not true of glycolysis?

    • Options
    • A. ADP is phosphorylated to ATP via substrate level phosphorylation
    • B. The pathway does not require oxygen
    • C. The pathway oxidizes two moles of NADH to NAD+ for each mole of glucose that enters
    • D. The pathway requires two moles of ATP to get started catabo-lizing each mole of glucose
    • Discuss
    • 8. During catabolism, only about 40% of the energy available from oxidizing glucose is used to synthesize ATP. Remaining 60%

    • Options
    • A. is lost as heat
    • B. is used to reduce NADP
    • C. remains in the products of metabolism
    • D. is stored as fat.
    • Discuss
    • 9. For every one molecule of sugar glucose which is oxidized __________ molecule of pyruvic acid are produced.

    • Options
    • A. 1
    • B. 2
    • C. 3
    • D. 4
    • Discuss
    • 10. The amount of energy received from one ATP is

    • Options
    • A. 76 kcal
    • B. 7.3 kcal
    • C. 760 kcal
    • D. 1000 kcal
    • Discuss


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