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Home Biochemistry Protein Structure Comments

  • Question
  • Over 50% of common cancers are associated with damage to a protein, p53. This protein


  • Options
  • A. is a cyclin
  • B. is a tumor supressor
  • C. is an oncogene
  • D. regulates apoptosis

  • Correct Answer
  • is a tumor supressor 


  • Protein Structure problems


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    • 1. Cyclins are proteins that

    • Options
    • A. regulate ability of cells to invade tissue
    • B. regulate passage from one stage of cell division to another
    • C. regulate apoptosis of damaged cells
    • D. none of the above
    • Discuss
    • 2. Individuals with PKU disease are mentally retarded unless

    • Options
    • A. phenylalanine in the diet is restricted
    • B. tyrosine in the diet is restricted
    • C. homogentisic acid in the diet is restricted
    • D. none of the above
    • Discuss
    • 3. BRACl, an inherited form of breast cancer, regulates cell division by

    • Options
    • A. binding to a DNA sequence
    • B. complexing with cyclins
    • C. binding to the cell outer membrane
    • D. binding to the protein RAD 51 which repairs DNA damage
    • Discuss
    • 4. Marfan's syndrome is thought to be a mutation affecting

    • Options
    • A. hemoglobin synthesis
    • B. collagen synthesis
    • C. metabolism of homogentisic acid
    • D. insufficient thyroid production
    • Discuss
    • 5. The major function of RNA polymerase's sigma factor is

    • Options
    • A. recognition of the translational stop sequence
    • B. recognition of the transcriptional start sequence
    • C. recognition of the transcriptional stop sequence
    • D. recognition of the translational start sequence
    • Discuss
    • 6. The four subunits of the hemoglobin (Hb) gene represent protein's

    • Options
    • A. primary structure
    • B. secondary structure
    • C. tertiary structure
    • D. quaternary structure
    • Discuss
    • 7. Beta pleated sheets are examples of protein's

    • Options
    • A. primary structure
    • B. secondary structure
    • C. tertiary structure
    • D. quaternary structure
    • Discuss
    • 8. Metastasis involves

    • Options
    • A. ability of cells to dissolve cellular matrix
    • B. metalloprotein levels
    • C. decreased levels of proteins that regulate metalloproteins
    • D. all of the above
    • Discuss
    • 9. Sickle cell disease is due to

    • Options
    • A. a mutation in the beta chain of Hb
    • B. a mutation in the alpha chain of Hb
    • C. infection with a parasite
    • D. none of the above
    • Discuss
    • 10. Signal sequences are part of a protein that

    • Options
    • A. signal folding of the protein
    • B. signal the protein synthesis on the ribosomes is ended
    • C. transport proteins to other sites within the cell
    • D. refold proteins in prion-associated diseases
    • Discuss


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