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Home Biochemistry Allosteric Effects Comments

  • Question
  • A protein that shows infinite cooperative for binding of n ligands will


  • Options
  • A. show a Hill coefficient (nH) of 0.0
  • B. only be found in either the unliganded form or the fully liganded form
  • C. show a Hill coefficient (nH) of n
  • D. both (b) and (c)

  • Correct Answer
  • both (b) and (c) 


  • Allosteric Effects problems


    Search Results


    • 1. Small molecules affect hemoglobin (Hb) by

    • Options
    • A. decreasing Hb affinity for O2
    • B. increasing [H+]
    • C. increasing Hb affinity for O2
    • D. increasing [H+] and decreasing Hb affinity for O2
    • Discuss
    • 2. Bisphosphoglycerate (BPG) cannot bind to the oxygenated R state of hemoglobin because

    • Options
    • A. it is displaced from the heme by oxygen
    • B. it is displaced from the heme by movement of the proximal histidine
    • C. its binding pocket becomes too small to accommodate BPG
    • D. BPG binds to the R state with the same affinity as the T state
    • Discuss
    • 3. In hemoglobin, allosteric effects occur

    • Options
    • A. only in humans
    • B. for maintaining Fe in the Fe2+ state
    • C. to minimize oxygen delivery to the tissues
    • D. to maximize oxygen delivery to the tissues
    • Discuss
    • 4. O2 binding to hemoglobin results in

    • Options
    • A. 100-fold higher affinity for the last O2 bound than for the first
    • B. extensive protein conformational change
    • C. both (a) and (b)
    • D. 100-fold lower affinity for the last O2 bound than for the first
    • Discuss
    • 5. A protein that binds two ligands in a non-cooperative manner will show

    • Options
    • A. a sigmodial binding curve
    • B. a hyperbolic binding curve
    • C. a linear Scatchard Plot
    • D. both (b) and (c)
    • Discuss
    • 6. Which of the following is most likely to produce anaphylaxis in a susceptible individual?

    • Options
    • A. Pollen
    • B. Mold
    • C. Dust
    • D. Bee sting
    • Discuss
    • 7. The maturation of T cells and the production of particular T cell receptors occurs in the

    • Options
    • A. thyroid gland
    • B. thymus gland
    • C. testes
    • D. all of these
    • Discuss
    • 8. Which of the following produces the antibodies employed in the specific immune response of vertebrates?

    • Options
    • A. B lymphocytes
    • B. T lymphocytes
    • C. Neutrophils
    • D. Macrophages
    • Discuss
    • 9. Which of these is part of the lymphoid system in humans?

    • Options
    • A. Liver
    • B. Stomach
    • C. Tonsils
    • D. Kidneys
    • Discuss
    • 10. Which of these is a type of specific defense against pathogens?

    • Options
    • A. Lymphocytes
    • B. Macrophages
    • C. Phagocytes
    • D. Leukocytes
    • Discuss


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