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Biochemistry
‣
DNA Structure and Replication
Comments
Question
The rapid appearance of HIV-1 strains that are resistant to AIDS drugs is due in part to which of the following property of its reverse transcriptase?
Options
A. AZT (zidovudine) is too expensive to be taken in effective doses
B. The RNase H domain of p66 causes error prone synthesis
C. It lacks a proofreading exonuclease
D. It has low affinity for the correct dNTP's
Correct Answer
It lacks a proofreading exonuclease
DNA Structure and Replication problems
Search Results
1. The nicks or gaps between Okazaki fragments are eventually sealed by
Options
A. gyrase
B. DNA ligase
C. RNA ligase
D. polymerase
Show Answer
Scratch Pad
Discuss
Correct Answer: DNA ligase
2. Each replication bubbles consists of
Options
A. 3 replication forks
B. 2 replication forks
C. 4 replication forks
D. 1 replication forks
Show Answer
Scratch Pad
Discuss
Correct Answer: 2 replication forks
3. The packing ratio of nucleosomes is about
Options
A. 6
B. 8
C. 7
D. 9
Show Answer
Scratch Pad
Discuss
Correct Answer: 7
4. The enzyme responsible for breaking the hydrogen bonds, and thus separating the DNA strands during DNA synthesis is
Options
A. DNA polymerase
B. strandase
C. helicase
D. none of these
Show Answer
Scratch Pad
Discuss
Correct Answer: helicase
5. Which of the following species lack a 'classical' histone H1?
Options
A.
Saccharomyces cerevisiae
B.
Strongylocentrotus purpuratus
C.
Xenopus laevis
D.
Arabidopsis thaliana
Show Answer
Scratch Pad
Discuss
Correct Answer:
Saccharomyces cerevisiae
6. 30 nm wide helix with five or six nucleosomes per helix is known as
Options
A. solenoid
B. halonoid
C. kinoplast
D. none of these
Show Answer
Scratch Pad
Discuss
Correct Answer: solenoid
7. What is the approximate percentage of repetitive DNA sequences in human DNA?
Options
A. 10 to 20%
B. 20 to 30%
C. 30 to 40%
D. 40 to 50%
Show Answer
Scratch Pad
Discuss
Correct Answer: 20 to 30%
8. Okazaki fragments occur on the __________ and are bonded together by __________
Options
A. Leading strand, polymerase
B. mRNA, anticodons
C. Lagging strand, ligase
D. tRNA, polymerase
Show Answer
Scratch Pad
Discuss
Correct Answer: Lagging strand, ligase
9. Overwinding or overtightening of DNA during replication is caused and removed by
Options
A. DNAb, DNA polymerase
B. DNAa, gyrase
C. DNAb, gyrase
D. Single stranded protein, DNAa
Show Answer
Scratch Pad
Discuss
Correct Answer: DNAb, gyrase
10. In a cesium chloride gradient, DNA labeled with
15
N and centrifuged will form a band
Options
A. above DNA containing
14
N
B. below DNA containing
14
N
C. with
14
N-containing DNA
D. all of these
Show Answer
Scratch Pad
Discuss
Correct Answer: below DNA containing
14
N
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Cell Signalling and Transduction
Cell Structure and Compartments
Chromatography
Disease Associated with Immune System
DNA Structure and Replication
Enzymes
FT IR Spectroscopy
Gas Chromatography
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Genetic Code and Regulation
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Glycolysis
HPLC
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Immune System
Immunological Techniques
Lipid
Membrane Structure and Functions
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NMR Spectroscopy
Nucleic Acids
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Photosynthesis and Respiration
Polymerase Chain Reaction
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Protein Purification
Protein Stability
Protein Structure
Protein Synthesis
Recombinant DNA Technology
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Spectroscopy
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Thermodynamics and Free Energy
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