Discussion
Home ‣ Biochemistry ‣ DNA Structure and Replication Comments
- Question
The enzyme responsible for breaking the hydrogen bonds, and thus separating the DNA strands during DNA synthesis is
Options- A. DNA polymerase
- B. strandase
- C. helicase
- D. none of these
- Correct Answer
- helicase
- 1. Which of the following species lack a 'classical' histone H1?
Options- A. Saccharomyces cerevisiae
- B. Strongylocentrotus purpuratus
- C. Xenopus laevis
- D. Arabidopsis thaliana Discuss
- 2. The replication of a linear DNA molecule in a eukaryotic chromosome creates a problem which is reported to be sorted out by
Options- A. using enzyme called telomerase
- B. shortening of the double stranded replicated portion
- C. using RNA as a template
- D. none of the above Discuss
- 3. The role of primase is to
Options- A. dismantle RNA primer
- B. cleave and unwinds short sections of DNA ahead of the replication fork
- C. proofread base pairing
- D. synthesize an RNA primer to begin the elongation process Discuss
- 4. In DNA replication, one new strand is synthesized complementary to an old (parent) strand and is referred as
Options- A. mutational
- B. semiconservative
- C. discontinuous
- D. antiparallel Discuss
- 5. The melting of 40-45 bp at the oriC site of E. coli requires
Options- A. DNA + ATP + HU
- B. DNA + ATP + HU + DNAb
- C. DNA+ ATP + HU + DNAb + DNAa
- D. DNA + ATP + HU + DNAb + DNAa + Pol III holoenzyme Discuss
- 6. The packing ratio of nucleosomes is about
Options- A. 6
- B. 8
- C. 7
- D. 9 Discuss
- 7. Each replication bubbles consists of
Options- A. 3 replication forks
- B. 2 replication forks
- C. 4 replication forks
- D. 1 replication forks Discuss
- 8. The nicks or gaps between Okazaki fragments are eventually sealed by
Options- A. gyrase
- B. DNA ligase
- C. RNA ligase
- D. polymerase Discuss
- 9. The rapid appearance of HIV-1 strains that are resistant to AIDS drugs is due in part to which of the following property of its reverse transcriptase?
Options- A. AZT (zidovudine) is too expensive to be taken in effective doses
- B. The RNase H domain of p66 causes error prone synthesis
- C. It lacks a proofreading exonuclease
- D. It has low affinity for the correct dNTP's Discuss
- 10. 30 nm wide helix with five or six nucleosomes per helix is known as
Options- A. solenoid
- B. halonoid
- C. kinoplast
- D. none of these Discuss
DNA Structure and Replication problems
Search Results
Correct Answer: Saccharomyces cerevisiae
Correct Answer: using enzyme called telomerase
Correct Answer: synthesize an RNA primer to begin the elongation process
Correct Answer: semiconservative
Correct Answer: DNA + ATP + HU
Correct Answer: 7
Correct Answer: 2 replication forks
Correct Answer: DNA ligase
Correct Answer: It lacks a proofreading exonuclease
Correct Answer: solenoid
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