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Home Biochemistry DNA Structure and Replication Comments

  • Question
  • Which of the following species lack a 'classical' histone H1?


  • Options
  • A. Saccharomyces cerevisiae
  • B. Strongylocentrotus purpuratus
  • C. Xenopus laevis
  • D. Arabidopsis thaliana

  • Correct Answer
  • Saccharomyces cerevisiae 


  • DNA Structure and Replication problems


    Search Results


    • 1. The replication of a linear DNA molecule in a eukaryotic chromosome creates a problem which is reported to be sorted out by

    • Options
    • A. using enzyme called telomerase
    • B. shortening of the double stranded replicated portion
    • C. using RNA as a template
    • D. none of the above
    • Discuss
    • 2. The role of primase is to

    • Options
    • A. dismantle RNA primer
    • B. cleave and unwinds short sections of DNA ahead of the replication fork
    • C. proofread base pairing
    • D. synthesize an RNA primer to begin the elongation process
    • Discuss
    • 3. In DNA replication, one new strand is synthesized complementary to an old (parent) strand and is referred as

    • Options
    • A. mutational
    • B. semiconservative
    • C. discontinuous
    • D. antiparallel
    • Discuss
    • 4. The melting of 40-45 bp at the oriC site of E. coli requires

    • Options
    • A. DNA + ATP + HU
    • B. DNA + ATP + HU + DNAb
    • C. DNA+ ATP + HU + DNAb + DNAa
    • D. DNA + ATP + HU + DNAb + DNAa + Pol III holoenzyme
    • Discuss
    • 5. One hypothesis of DNA replication suggested that the parental DNA molecules are broken into fragments. Both strands of DNA in each of the daughter molecules are made up of an assortment of parental and new DNA. This statement refers to which hypothesis?

    • Options
    • A. Conservative theory
    • B. Dispersive theory
    • C. Semi-conservative theory
    • D. Evolutionary theory
    • Discuss
    • 6. The enzyme responsible for breaking the hydrogen bonds, and thus separating the DNA strands during DNA synthesis is

    • Options
    • A. DNA polymerase
    • B. strandase
    • C. helicase
    • D. none of these
    • Discuss
    • 7. The packing ratio of nucleosomes is about

    • Options
    • A. 6
    • B. 8
    • C. 7
    • D. 9
    • Discuss
    • 8. Each replication bubbles consists of

    • Options
    • A. 3 replication forks
    • B. 2 replication forks
    • C. 4 replication forks
    • D. 1 replication forks
    • Discuss
    • 9. The nicks or gaps between Okazaki fragments are eventually sealed by

    • Options
    • A. gyrase
    • B. DNA ligase
    • C. RNA ligase
    • D. polymerase
    • Discuss
    • 10. The rapid appearance of HIV-1 strains that are resistant to AIDS drugs is due in part to which of the following property of its reverse transcriptase?

    • Options
    • A. AZT (zidovudine) is too expensive to be taken in effective doses
    • B. The RNase H domain of p66 causes error prone synthesis
    • C. It lacks a proofreading exonuclease
    • D. It has low affinity for the correct dNTP's
    • Discuss


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