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  • Question
  • In column switching chromatography


  • Options
  • A. compounds trapped on one column are eluted to another column
  • B. one column is removed and replaced by another
  • C. the flow to the column is switched on and off repeatedly
  • D. any of the above

  • Correct Answer
  • compounds trapped on one column are eluted to another column 


  • Gas Chromatography problems


    Search Results


    • 1. Derivatisation of a sample is carried out to

    • Options
    • A. reduce polarity of the analytes
    • B. increase the detector response
    • C. increase volatility of the analytes
    • D. all of the above
    • Discuss
    • 2. What are the benefits of decreasing the column internal diameter?

    • Options
    • A. Increased sample capacity
    • B. Increased resolution
    • C. Reduced risk of column overloading
    • D. All of the above
    • Discuss
    • 3. Sample injection is considered successful if

    • Options
    • A. all of the sample in the injector has been added to the column
    • B. the sample is concentrated at the start of the column
    • C. the sample is spread evenly along the column
    • D. the sample is homogenously spread along the column
    • Discuss
    • 4. Sample retention in the column is measured by

    • Options
    • A. retention time
    • B. retention factor
    • C. retention index
    • D. all of these
    • Discuss
    • 5. What does the retention factor, k', describe?

    • Options
    • A. The distribution of an analyte between the stationary and the mobile phase
    • B. The migration rate of an analyte through a column
    • C. The velocity of the mobile phase
    • D. All of these
    • Discuss
    • 6. Resolution is proportional to the

    • Options
    • A. number of theoretical plates in a column
    • B. square root of the number of theoretical plates in a column
    • C. square of the number of theoretical plates in a column
    • D. cube root of the number of theoretical plates in a column
    • Discuss
    • 7. The column is heated to

    • Options
    • A. prevent analyte condensation within the column
    • B. control elution of the different analytes
    • C. reduce band broadening to get sharper peaks
    • D. all of these
    • Discuss
    • 8. Which of the following detectors give mass flow-dependent signals?

    • Options
    • A. Electron capture detector
    • B. Field ionisation detector
    • C. Thermal conductivity detector
    • D. All of the above
    • Discuss
    • 9. Which of the following is not used for detection in GC?

    • Options
    • A. Infrared spectroscopy
    • B. NMR
    • C. Flame ionisation
    • D. Electrical conductivity
    • Discuss
    • 10. Which of these effects result from slow injection of a large sample volume?

    • Options
    • A. Increased resolution
    • B. Decreased resolution
    • C. Non-linear detector response
    • D. Constant resolution
    • Discuss


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