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Biochemistry
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Cell Signalling and Transduction
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Question
The enzyme that catalyzes the splitting of PIP2 into two molecules of inositol triphosphate (IP3) and diacylglycerol in cell signaling, is
Options
A. phosphokinase C
B. phospholipase C
C. phosphodiesterase C
D. lipokinase
Correct Answer
phospholipase C
Cell Signalling and Transduction problems
Search Results
1. The binding of ligands to many G-proteins linked receptors leads to shortlived
Options
A. increase in the concentration of certain intracellular signaling molecules called second messenger
B. decrease in the concentration of certain intracellular signaling molecules called second messenger
C. increase in the concentration of certain extracellular signaling molecules called first messenger
D. decrease in the concentration of certain extracellular signaling molecules called first messenger
Show Answer
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Correct Answer: increase in the concentration of certain intracellular signaling molecules called second messenger
2. Simple nerve reflexes use signaling molecules called
Options
A. neurotransmitters
B. nitric oxides
C. G proteins
D. proteases
Show Answer
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Discuss
Correct Answer: neurotransmitters
3. The major second messengers are
Options
A. cAMP
B. cGMP
C. DAG
D. All of these
Show Answer
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Discuss
Correct Answer: All of these
4. Cell signaling can be classified into
Options
A. three distinct types based on the distance over which the signaling molecules act
B. two distinct types based on the distance over which the signaling molecules act
C. three distinct types based on the signaling molecules
D. none of the above
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Correct Answer: three distinct types based on the distance over which the signaling molecules act
5. The hormone or ligand can be considered as
Options
A. first messenger
B. second messenger
C. both (a) and (b)
D. none of these
Show Answer
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Correct Answer: first messenger
6. Which of the following statement is incorrect?
Options
A. The principal lipophilic hormones that binds to receptors located in the plasma membranes are prostaglandins
B. Prostaglandins are synthesized from arachidonic acid
C. Prostaglandins act as paracrine signaling molecules
D. None of the above
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Correct Answer: None of the above
7. In paracrine signaling, the signaling molecules affects only
Options
A. target cells close to the cell from which it was secreted
B. target cells distant from its site of synthesis in cells of an endocrine organ
C. both (a) and (b)
D. none of the above
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Correct Answer: target cells close to the cell from which it was secreted
8. A signal cascade induced by adrenaline or thyroxine
Options
A. must begin with receipt of the signal molecule by a surface receptor
B. involves the activation of a G protein
C. results in the activation of a sequence of enzymes needed for the cell effect
D. all of the above
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Correct Answer: all of the above
9. Self-phosphorylation is an excellent mechanism for triggering specific catalytic function of the proteins involved in signal cascades because it
Options
A. changes the shape and thus the enzymatic activity of the proteins involved
B. makes the receptor more likely to capture the signaling, molecule
C. allows hydrophilic signaling molecules to cross the plasma membrane
D. None of the above
Show Answer
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Correct Answer: changes the shape and thus the enzymatic activity of the proteins involved
10. Which of the following is not a type of signaling molecule?
Options
A. Testosterone
B. Insulin
C. Thyroxin
D. Adenylate cyclase
Show Answer
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Discuss
Correct Answer: Adenylate cyclase
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