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Home Biochemistry ATP Synthesis and Fatty Acid Oxidation Comments

  • Question
  • The irreversibility of the thiokinase reactions (formation of initial acyl-CoA)


  • Options
  • A. make this activation reaction the committed step on the pathway
  • B. is due to the subsequent hydrolysis of the product
  • C. applies only to even-chain fatty acids
  • D. both (a) and (b)

  • Correct Answer
  • both (a) and (b) 


  • ATP Synthesis and Fatty Acid Oxidation problems


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    • 1. How many molecules of acetyl-CoA are produced in oxidation of palmitic acid (C16), which involves seven rounds of oxidation?

    • Options
    • A. 6
    • B. 7
    • C. 8
    • D. 9
    • Discuss
    • 2. The three identical b subunits of the F1, complex during ATP synthesis have

    • Options
    • A. different affinities for ATP but not for ADP
    • B. different affinities for ADP but not for ATP
    • C. different affinities for ATP and for ADP
    • D. similar affinities for ADP and ATP
    • Discuss
    • 3. Membrane potential and the proton gradient

    • Options
    • A. are both required to make ATP
    • B. are sufficient, separately, to make ATP from ADP + Pi;
    • C. reinforce one another when respiratory inhibitors are present
    • D. cancel one another when uncouplers are present
    • Discuss
    • 4. Long-chain fatty acids are oxidized step-wise in one carbon units starting from the

    • Options
    • A. carboxyl end
    • B. aliphatic end
    • C. both (a) and (b)
    • D. none of these
    • Discuss
    • 5. Each cycle of ?-oxidation produces

    • Options
    • A. 1 FADH2, 1 NAD+, and 1 acetyl-CoA
    • B. 1 FADH2, 1 NADH and 1 acetyl-CoA
    • C. 1 FADH2, 1 NADH and 2 CO2 molecules
    • D. 1 FAD, 1 NAD+ and 2 CO2 molecules
    • Discuss
    • 6. Which of the following is not a feature of oxidative phosphorylation?

    • Options
    • A. Direct transfer of phosphate from a substrate molecule to ADP
    • B. An electrochemical gradient across the inner mitochondrial membrane
    • C. A membrane bound ATP synthase
    • D. A protonmotive force
    • Discuss
    • 7. In aerobic respiration, the compound that enters a mitochondrion is

    • Options
    • A. acetyl CoA
    • B. pyruvate
    • C. phosphoglyceraldehyde
    • D. oxaloacetate
    • Discuss
    • 8. How many CO2 molecules are exhaled for each O2 molecule utilized in cellular respiration?

    • Options
    • A. 1
    • B. 3
    • C. 6
    • D. 12
    • Discuss
    • 9. Coenzyme Q is involved in electron transport as

    • Options
    • A. directly to O2
    • B. a water-soluble electron donor
    • C. covalently attached cytochrome cofactor
    • D. a lipid-soluble electron carrier
    • Discuss
    • 10. A biological redox reaction always involves

    • Options
    • A. an oxidizing agent
    • B. a gain of electrons
    • C. a reducing agent
    • D. all of these
    • Discuss


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