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Home Biochemistry Anti Bodies Comments

  • Question
  • The immunoglobulin fold is


  • Options
  • A. found only in IgG molecules
  • B. a ?-barrel composed of a three- and a four-stranded antiparallel ?-sheet
  • C. both (a) and (b)
  • D. found six times in the IgG molecule

  • Correct Answer
  • a ?-barrel composed of a three- and a four-stranded antiparallel ?-sheet 


  • Anti Bodies problems


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    • 1. A polyclonal antibody response

    • Options
    • A. is produced only in response to polymeric antigens
    • B. is produced by several B cells recognizing different pitopes on the same antigen
    • C. occurs during the lag phase of the immune response
    • D. violates clonal selection
    • Discuss
    • 2. Antibodies in the human immune system can identify approximately 108 different molecules Which one of the following is correct?

    • Options
    • A. This diversity is generated from 108 different immunoglobin genes
    • B. Many of these molecules are self-antigens
    • C. Most of these antibodies recognize proteins
    • D. Most of these antibodies recognize small organic molecules
    • Discuss
    • 3. Papain digest IgG into

    • Options
    • A. two Fab fragments and one Fc fragment
    • B. three Fab fragments and two Fc fragments
    • C. two Fab fragments and two Fc fragments
    • D. three Fab fragments and three Fc fragments
    • Discuss
    • 4. Each IgA antibody molecule consists of

    • Options
    • A. four polypeptide chain and has two antigen binding site
    • B. two polypeptide chain and has one antigen binding site
    • C. three polypeptide chain and has two antigen binding site
    • D. two polypeptide chain and has two antigen binding site
    • Discuss
    • 5. Which of the following are responsible for immune specificity?

    • Options
    • A. Antigens
    • B. Antibodies
    • C. T lymphocytes
    • D. Macrophage
    • Discuss
    • 6. The main function of antibodies is to

    • Options
    • A. kill all the foreign bodies
    • B. generate antigens, thus conferring immunization
    • C. protect the circulatory system
    • D. chemically combine with the antigen which induces it, inactivate the antigen and protect the body from disease
    • Discuss
    • 7. IgE provides

    • Options
    • A. immunity against some parasites
    • B. complement killings of the cells and phagocytosis
    • C. secretions in the body
    • D. all of the above
    • Discuss
    • 8. Alum is an effective adjuvant because it

    • Options
    • A. disaggregates the antigen.
    • B. is immunogenic for stem cells
    • C. is immunogenic for T cells
    • D. slows the release of antigen
    • Discuss
    • 9. Antigenic determinants bind to which portions of an antibody?

    • Options
    • A. Variable regions
    • B. Constant regions
    • C. Only light chains
    • D. Only heavy chains
    • Discuss
    • 10. Structures of anti-PCP antibody shows that the tight binding of PCP to the antibody is primarily due to

    • Options
    • A. hydrophobic forces
    • B. electrostatic forces.
    • C. Van der Waals forces.
    • D. none of these
    • Discuss


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