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Home Biotechnology Monoclonal Antibodies Comments

  • Question
  • The cross linkage of antigens by antibodies is known as


  • Options
  • A. agglutination
  • B. complement fixation
  • C. a cross reaction
  • D. all of these

  • Correct Answer
  • agglutination 


  • Monoclonal Antibodies problems


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    • 1. TC cells are important in controlling

    • Options
    • A. virus infections
    • B. allergy
    • C. autoimmunity
    • D. all of these
    • Discuss
    • 2. It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at

    • Options
    • A. high frequencies
    • B. moderate frequencies
    • C. low frequencies
    • D. at no frequency
    • Discuss
    • 3. The antigen-specific lymphocytes can be immortalized by which of the following method?

    • Options
    • A. Transfection with tumor derived DNA
    • B. Hybridization with a suitable lymphoid tumor cell
    • C. Transformation following infection by Epstein-Barr virus (EB V)
    • D. All of the above
    • Discuss
    • 4. In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc.,

    • Options
    • A. T8 cells are greatly reduced
    • B. T8 cells are greatly increased
    • C. T4 cells are greatly reduced
    • D. T4 cells are greatly increased
    • Discuss
    • 5. The approach (s), which is/are currently followed to produce human monoclonal antibodies, is/are known as

    • Options
    • A. transformation of antigen specific B lymphocytes (EBV)
    • B. hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes
    • C. combination of EB Vand hybridoma techniques
    • D. all of these
    • Discuss
    • 6. The Ig locus is about

    • Options
    • A. 2/3rd of all hybridomas
    • B. l/3rd of all hybridomas
    • C. l/2nd of all hybridomas
    • D. 1/4th of all hybridomas
    • Discuss
    • 7. Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with

    • Options
    • A. Ig MAbs
    • B. IgG
    • C. IgA
    • D. IgE
    • Discuss
    • 8. Small simple molecules are

    • Options
    • A. poor antigens
    • B. rich antigens
    • C. moderate antigens
    • D. heterophilic antigens
    • Discuss
    • 9. In human B cells and T cells are matured in the

    • Options
    • A. bone marrow and thymus respectively
    • B. lymph nodes and spleen respectively
    • C. bursa and thymus respectively
    • D. none of these
    • Discuss
    • 10. T cells are the source of

    • Options
    • A. interleukin
    • B. interferon
    • C. lymphotoxin
    • D. all of these
    • Discuss


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