Disorders problems
- 1. Which of the modification in hemoglobin is the cause of sickle cell anemia?
Options- A. A mutation in the beta chain
- B. A deletion in the beta chain
- C. Replacement of the B chain by D chain
- D. None of the above Discuss
Correct Answer: A mutation in the beta chain
- 2. Which of the protein is involved in Alzheimer's disease?
Options- A. A4
- B. Amylin
- C. Fibrin
- D. Alzhemin Discuss
Correct Answer: A4
- 3. A deficiency of the enzyme Hypoxanthine Guanine phosphoribosyl transferase (HGPRT) may cause
Options- A. Gaucher's disease
- B. Ehlers-Danlos syndrome
- C. Lesch- Nyhan syndrome
- D. Kleinefelter's syndrome Discuss
Correct Answer: Lesch- Nyhan syndrome
- 4. The disorder in which of the following may cause "Ehlers-Danlos Syndrome"?
Options- A. Dlashin protein
- B. Collagen protein
- C. Fibrin protein
- D. Globulin protein Discuss
Correct Answer: Collagen protein
- 5. Methotrexate is toxic to human cells because it inhibits
Options- A. formation of CTP from UTP
- B. reduction of H2 folate to H4 folate
- C. synthesis of PRPP
- D. none of the above Discuss
Correct Answer: reduction of H2 folate to H4 folate
- 6. During sickle cell anemia which of the following takes place?
Options- A. Glutamine change to valine
- B. Valine change to glutamine
- C. Aspartic acid change to glutamic acid
- D. Glutamic acid change to aspartic acid Discuss
Correct Answer: Glutamine change to valine
- 7. What is the defective enzyme in the glycogen storage Von Gierke's disease?
Options- A. Phosphorylase
- B. Phosphofructokinase
- C. Glucose-6-phosphatase
- D. None of the above Discuss
Correct Answer: Glucose-6-phosphatase
- 8. If the RBC of human were kept in 0.9% NaCl solution, what sort of change will occur to RBC?
Options- A. Cell will Burst
- B. Cell will shrink
- C. No change to RBC
- D. RBC will destroy Discuss
Correct Answer: No change to RBC
- 9. Which of the following sets belongs to a distinct class or category?
Options- A. Ribose, sucrose, glucose, fructose
- B. Sterols, waxes, fatty acids, amino acids.
- C. Oils, sterols, waxes, fats
- D. Nucleotide, nucleoside, nucleus, DNA Discuss
Correct Answer: Sterols, waxes, fatty acids, amino acids.
- 10. Klinefelter syndrome is a manifestation of which chromosome aneuploidy?
Options- A. XXX
- B. XYY
- C. XXY
- D. None of these Discuss
Correct Answer: XXY
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