Discussion
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- Question
It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at
Options- A. high frequencies
- B. moderate frequencies
- C. low frequencies
- D. at no frequency
- Correct Answer
- high frequencies
- 1. The antigen-specific lymphocytes can be immortalized by which of the following method?
Options- A. Transfection with tumor derived DNA
- B. Hybridization with a suitable lymphoid tumor cell
- C. Transformation following infection by Epstein-Barr virus (EB V)
- D. All of the above Discuss
- 2. In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc.,
Options- A. T8 cells are greatly reduced
- B. T8 cells are greatly increased
- C. T4 cells are greatly reduced
- D. T4 cells are greatly increased Discuss
- 3. The approach (s), which is/are currently followed to produce human monoclonal antibodies, is/are known as
Options- A. transformation of antigen specific B lymphocytes (EBV)
- B. hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes
- C. combination of EB Vand hybridoma techniques
- D. all of these Discuss
- 4. The EBV-hybridoma technique
Options- A. immortalizes the donor Bcells
- B. facilitates the proliferation of antigen specific B cells
- C. gives much higher hybridization frequencies
- D. all of the above Discuss
- 5. A cytokine that stimulates the activity of B and T cells is
Options- A. lymphotoxin
- B. interlukin-2
- C. interlukin-1
- D. all of these Discuss
- 6. TC cells are important in controlling
Options- A. virus infections
- B. allergy
- C. autoimmunity
- D. all of these Discuss
- 7. The cross linkage of antigens by antibodies is known as
Options- A. agglutination
- B. complement fixation
- C. a cross reaction
- D. all of these Discuss
- 8. The Ig locus is about
Options- A. 2/3rd of all hybridomas
- B. l/3rd of all hybridomas
- C. l/2nd of all hybridomas
- D. 1/4th of all hybridomas Discuss
- 9. Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with
Options- A. Ig MAbs
- B. IgG
- C. IgA
- D. IgE Discuss
- 10. Small simple molecules are
Options- A. poor antigens
- B. rich antigens
- C. moderate antigens
- D. heterophilic antigens Discuss
Monoclonal Antibodies problems
Search Results
Correct Answer: All of the above
Correct Answer: T8 cells are greatly reduced
Correct Answer: all of these
Correct Answer: all of the above
Correct Answer: interlukin-2
Correct Answer: all of these
Correct Answer: agglutination
Correct Answer: 2/3rd of all hybridomas
Correct Answer: Ig MAbs
Correct Answer: poor antigens
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