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Synthesis of Therapeutic Agents problems


  • 1. Chemically synthesized DNA sequences for the two chains are separately inserted into the plasmid pBR 322 by the side of

  • Options
  • A. ?-Galactosidase
  • B. galactokinase
  • C. acid phosphatase
  • D. glucokinase
  • Discuss
  • 2. The promoter used for cloning HBV surface antigen is

  • Options
  • A. galactokinase
  • B. alcohol dehydrogenase 1
  • C. ?-galactosidase
  • D. polyhedrin
  • Discuss
  • 3. Recombinant vaccine for Hepatitis B virus has been synthesized against which of the following antigen?

  • Options
  • A. Viral core antigen (HBcAg)
  • B. Viral surface antigen (HBsAg)
  • C. e antigen (HBeAg)
  • D. All of the above
  • Discuss
  • 4. Foot and mouth disease (FMD) of animals is caused by

  • Options
  • A. RNA virus
  • B. DNA virus
  • C. bacteria
  • D. protozoa
  • Discuss
  • 5. In India first genetically engineered vaccine against HBV was developed by

  • Options
  • A. Ranbaxy Pvt Ltd
  • B. Shantha Biotechnics Pvt Ltd
  • C. Dabur Pvt Ltd
  • D. Glaxo Pvt Ltd
  • Discuss
  • 6. The first therapeutic product formed by means of recombinant DNA technology is

  • Options
  • A. human growth hormone
  • B. insulin
  • C. hepatitis B vaccine
  • D. vaccine for foot and mouth disease
  • Discuss
  • 7. The two chains of insulin can be separated by detaching it from ?-galactosidase using

  • Options
  • A. hydrogen chloride
  • B. cyanogen bromide
  • C. peptidase
  • D. protease
  • Discuss
  • 8. Human growth hormone (hGH) is secreted by

  • Options
  • A. pitutary gland
  • B. hypothalamus
  • C. pancreas
  • D. none of these
  • Discuss
  • 9. Recombinant vaccine for HBV was produced by cloning viral genes in

  • Options
  • A. plasmids
  • B. cosmids
  • C. autonomously replicating plasmid of yeast
  • D. phagemids
  • Discuss
  • 10. How is human insulin synthesized using recombinant DNA technology?

  • Options
  • A. By using chemically synthesized DNA sequences for the two chains separately
  • B. By isolating DNA from the islets of Langerhans of pancreas
  • C. By using cDNA for insulin
  • D. By using chemically synthesized DNA sequences for the complete insulin protein
  • Discuss

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