Antibiotics problems
- 1. At normal pH, penicillin remains in
Options- A. aqueous phase
- B. solvent phase
- C. both (a) and (b)
- D. precipitates Discuss
Correct Answer: aqueous phase
- 2. Fermentation medium for oxytetracyclin (terramycin) consist of
Options- A. CSL, starch, (NH4)2 SO4, sodium chloride and CaCO3
- B. CSL, (NH4)2 SO4, sodium chloride and CaCO3
- C. CSL, starch,(NH4)2 SO4, ammonium chloride and CaCO3
- D. CSL,(NH4)2 SO4, ammonium chloride and CaCO3 Discuss
Correct Answer: CSL, starch, (NH4)2 SO4, sodium chloride and CaCO3
- 3. Which of the following precursor is added in the medium to get penicillin G?
Options- A. Phenyl carbamic acid
- B. Phenyl acetic acid
- C. Ammonium sulphate
- D. Ammonium chloride Discuss
Correct Answer: Phenyl acetic acid
- 4. Antibiotics are typically produced in fed batch reactors because
Options- A. antibiotic yields are generally higher when cells enter the stationary phase
- B. the precursors are often toxic to the cells
- C. antibiotic yields are generally higher when cell growth slows
- D. All of the above Discuss
Correct Answer: All of the above
- 5. Media composition for the production of streptomycin is
Options- A. soybean meal, glucose, peptone, malt extract, sodium chloride
- B. soybean meal, glucose, peptone, malt extract, ammonium chloride
- C. soybean meal, glucose, peptone, malt extract, calcium carbonate
- D. soybean meal, glucose, peptone, malt extract, ammonium sulphate Discuss
Correct Answer: soybean meal, glucose, peptone, malt extract, sodium chloride
- 6. The yield of the antibiotic depends upon
Options- A. pH of the medium
- B. age of the inoculum
- C. composition of the medium
- D. all of these Discuss
Correct Answer: all of these
- 7. Chlorotetracyclin is soluble in
Options- A. organic solvents
- B. water
- C. ether
- D. all of these Discuss
Correct Answer: water
- 8. During which phase of growth of Penicillium chrysogenum maximum antibiotic production takes place
Options- A. during the first phase
- B. during the second phase
- C. during the third phase
- D. same in all the phases Discuss
Correct Answer: during the second phase
- 9. pH of the fermentation medium for chlorotetracyclins is
Options- A. 5-6
- B. 6-7
- C. 7-8
- D. 8-9 Discuss
Correct Answer: 5-6
- 10. Media used for the production of chlorotetracyclin consists of
Options- A. sugar, corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl
- B. corn steep liquor, CaCO3 and (NH4)2SO4
- C. sugar, CaCO3 and (NH4)2SO4
- D. corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl Discuss
Correct Answer: sugar, corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl
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