Discussion
Home ‣ Biotechnology ‣ Monoclonal Antibodies Comments
- Question
The antigen-specific lymphocytes can be immortalized by which of the following method?
Options- A. Transfection with tumor derived DNA
- B. Hybridization with a suitable lymphoid tumor cell
- C. Transformation following infection by Epstein-Barr virus (EB V)
- D. All of the above
- Correct Answer
- All of the above
- 1. In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc.,
Options- A. T8 cells are greatly reduced
- B. T8 cells are greatly increased
- C. T4 cells are greatly reduced
- D. T4 cells are greatly increased Discuss
- 2. The approach (s), which is/are currently followed to produce human monoclonal antibodies, is/are known as
Options- A. transformation of antigen specific B lymphocytes (EBV)
- B. hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes
- C. combination of EB Vand hybridoma techniques
- D. all of these Discuss
- 3. The EBV-hybridoma technique
Options- A. immortalizes the donor Bcells
- B. facilitates the proliferation of antigen specific B cells
- C. gives much higher hybridization frequencies
- D. all of the above Discuss
- 4. A cytokine that stimulates the activity of B and T cells is
Options- A. lymphotoxin
- B. interlukin-2
- C. interlukin-1
- D. all of these Discuss
- 5. In monoclonal antibody technology, tumor cells that can replicate endlessly are fused with mammalian cells that produce an antibody. The result of this cell fusion is a
Options- A. hybridoma
- B. myeloma
- C. natural killer cell
- D. lymphoblast Discuss
- 6. It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at
Options- A. high frequencies
- B. moderate frequencies
- C. low frequencies
- D. at no frequency Discuss
- 7. TC cells are important in controlling
Options- A. virus infections
- B. allergy
- C. autoimmunity
- D. all of these Discuss
- 8. The cross linkage of antigens by antibodies is known as
Options- A. agglutination
- B. complement fixation
- C. a cross reaction
- D. all of these Discuss
- 9. The Ig locus is about
Options- A. 2/3rd of all hybridomas
- B. l/3rd of all hybridomas
- C. l/2nd of all hybridomas
- D. 1/4th of all hybridomas Discuss
- 10. Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with
Options- A. Ig MAbs
- B. IgG
- C. IgA
- D. IgE Discuss
Monoclonal Antibodies problems
Search Results
Correct Answer: T8 cells are greatly reduced
Correct Answer: all of these
Correct Answer: all of the above
Correct Answer: interlukin-2
Correct Answer: hybridoma
Correct Answer: high frequencies
Correct Answer: all of these
Correct Answer: agglutination
Correct Answer: 2/3rd of all hybridomas
Correct Answer: Ig MAbs
Comments
There are no comments.More in Biotechnology:
Programming
Copyright ©CuriousTab. All rights reserved.