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Antimicrobial Chemotherapeutic Agents problems

  • 1. Most antibiotics are isolated from

  • Options
  • A. viruses
  • B. aquatic microorganisms
  • C. soil microorganisms
  • D. plants
  • Discuss
  • 2. Nystatin is a drug used for treatment of diseases caused by

  • Options
  • A. gram negative bacterium
  • B. gram positive bacterium
  • C. yeast
  • D. protozoan
  • Discuss
  • 3. Polyene antibiotics are

  • Options
  • A. large ring structures
  • B. ?-lactam - thiazolidine ring
  • C. small ring structures
  • D. any of these
  • Discuss
  • 4. Quinones and related antibiotics are

  • Options
  • A. tetracyclines
  • B. actinorhodin
  • C. mitomycin
  • D. all of these
  • Discuss
  • 5. Which antibiotic has a beta-lactam ring?

  • Options
  • A. Cephalosporin
  • B. Penicillin
  • C. Tetracycline
  • D. Streptomycin
  • Discuss
  • 6. Which of the following is not an aminoglycoside antibiotic?

  • Options
  • A. Streptomycin
  • B. Neomycin
  • C. Kanamycin
  • D. Cephalosporin
  • Discuss
  • 7. Which of the following is not a semi synthetic chemotherapeutic agent?

  • Options
  • A. Ampicillin
  • B. Carbenicillin
  • C. Penicillin
  • D. Sulfonamide
  • Discuss
  • 8. Cycloserine inhibits

  • Options
  • A. alanine racemase
  • B. D-alanyl - D-alanine synthetase
  • C. Both (a) and (b)
  • D. amidase
  • Discuss
  • 9. The larger the __________ , the better the chemotherapeutic agent.

  • Options
  • A. therapeutic index
  • B. therapeutic dose
  • C. selective toxicity
  • D. spectrum
  • Discuss
  • 10. By which of the following means antifungal chemotherapeutic agents may affect fungi?

  • Options
  • A. Interfere with nuclear division by preventing the aggregation of microtubules needed for mitosis
  • B. Interfere with normal nucleic acid synthesis
  • C. Interfere with ergosterol biosynthesis and thus alter the structure of the cytoplasmic membrane as well as the function of several membrane-bound enzymes like those involved in nutrient transport and chitin synthesis
  • D. all of these
  • Discuss

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