Translation and Regulation problems
- 1. The interaction between the mRNA and tRNA determined the position of amino acid in a polypeptide sequence. This is called the
Options- A. stagerivity
- B. Wobble hypothesis
- C. promiscuity
- D. adaptor hypothesis Discuss
Correct Answer: adaptor hypothesis
- 2. What is the direct cause of cell death by diphtheria toxin?
Options- A. Formation of an ion channel in the cell membrane
- B. Inactivation of a translational elongation factor
- C. Induction of apoptosis
- D. None of the above Discuss
Correct Answer: Inactivation of a translational elongation factor
- 3. When was the genetic code completed?
Options- A. 1958
- B. 1952
- C. 1966
- D. 1968 Discuss
Correct Answer: 1966
- 4. The ribosome binding site
Options- A. forms a stem-loop structure in the RNA
- B. is located upstream of the promoter sequence
- C. is located immediately upstream of the start codon
- D. is more likely to be associated with an operon than with a gene encoding a single protein Discuss
Correct Answer: is located immediately upstream of the start codon
- 5. Which of the following act as the blueprint or template for the process of protein synthesis that takes place on ribosomes?
Options- A. rRNA
- B. DNA
- C. tRNA
- D. mRNA Discuss
Correct Answer: mRNA
- 6. Three stop codons, which aids in termination of translation are also known as
Options- A. pause codons
- B. nonsense codons
- C. missense codons
- D. antisense codons Discuss
Correct Answer: nonsense codons
- 7. What is the action of tetracycline in prokaryotes?
Options- A. It blocks translocation reaction on ribosomes
- B. It blocks peptidyl transferase reaction on ribosomes
- C. It blocks the binding of amino-acyl tRNA to the A site of ribosomes
- D. Not known with certainity Discuss
Correct Answer: It blocks the binding of amino-acyl tRNA to the A site of ribosomes
- 8. What is the maximum number of different amino acids in a polypeptide chain coded by the synthetic polyribonucleotides (UCAG)5?
Options- A. One
- B. Two
- C. Three
- D. Four Discuss
Correct Answer: Three
- 9. Which binding is inhibited by pactamycin?
Options- A. Aminoacyl-tRNA to the A-site of 30S subunit
- B. Initiator-tRNA to 30S/40S initiation complexes
- C. Peptidyl t-RNA to the 50S subunit
- D. Formation of peptide bond in P site Discuss
Correct Answer: Initiator-tRNA to 30S/40S initiation complexes
- 10. Which stop codon has been found to encode selenocysteine?
Options- A. UAA
- B. UAG
- C. UGA
- D. AGA Discuss
Correct Answer: UGA
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