Antibody problems
- 1. The class of immunoglobulins which can cross the placenta is
Options- A. IgM
- B. IgG
- C. IgA
- D. IgD Discuss
Correct Answer: IgG
- 2. Heat-labile class of immunoglobulins include
Options- A. IgA
- B. IgE
- C. IgG
- D. IgM Discuss
Correct Answer: IgE
- 3. Which of the following (s) is/are function (s) of Fc fragment of IgG?
Options- A. It determines catabolic rate
- B. It binds complement
- C. It is related to passage of IgG across the placental barrier
- D. All of these Discuss
Correct Answer: All of these
- 4. J chain is present in
Options- A. IgA
- B. IgM
- C. Both (a) and (b)
- D. IgE Discuss
Correct Answer: Both (a) and (b)
- 5. Which is the most efficient complement fixing class of antibody?
Options- A. IgE
- B. IgA
- C. IgM
- D. IgG Discuss
Correct Answer: IgM
- 6. Which is not a function of IgG?
Options- A. Major antibody in serum
- B. First antibody type produced against an antigen during the primary antibody response
- C. Activates or fixes complement
- D. Involved in opsonization Discuss
Correct Answer: First antibody type produced against an antigen during the primary antibody response
- 7. Self reactive antibodies are not found in significant concentration in normal serum because
Options- A. it is impossible to generate a self-reactive antibody
- B. self reactive B cells are killed by CD8 T cells
- C. B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide
- D. self reactive B cells switch to IgA which is all secreted and not present in serum Discuss
Correct Answer: B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide
- 8. Antigen binding sites of an immunoglobulin are located in
Options- A. light chain alone
- B. heavy chain alone
- C. Fc region of the antibody
- D. Fab regions of the antibody Discuss
Correct Answer: Fab regions of the antibody
- 9. Which of the following theory of antibody production is most widely accepted?
Options- A. Side chain theory
- B. Clonal selection theory
- C. Direct template theory
- D. Indirect template theory Discuss
Correct Answer: Clonal selection theory
- 10. Which is not a function of IgA?
Options- A. Protect mucosal surfaces
- B. Fix complement
- C. Protect eyes
- D. Agglutinate antigen Discuss
Correct Answer: Fix complement
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