Antimicrobial Chemotherapeutic Agents problems
- 1. The susceptibility of a microorganism to antibiotics and other chemotherapeutic agents can be determined by using
Options- A. tube dilution technique
- B. paper disk plate
- C. both (a) and (b)
- D. none of these Discuss
Correct Answer: both (a) and (b)
- 2. Chemotherapeutic agents must
Options- A. prevent/destroy the activity of a parasite
- B. leave unaltered the host's natural defense mechanisms
- C. be able to come in contact with the parasite by penetrating the cells
- D. all of the above Discuss
Correct Answer: all of the above
- 3. Which of the following is used only in life-threatening situations when no other drug is adequate?
Options- A. Penicillin
- B. Tetracycline
- C. Chloramphenicol
- D. Streptomycin Discuss
Correct Answer: Chloramphenicol
- 4. Which of the following drugs involves modification of the drug by enzymatic modification or degradation of its active element to alter its/their resistance?
Options- A. Pencillins
- B. Choloramphenicol
- C. Aminoglyosides
- D. All of these Discuss
Correct Answer: All of these
- 5. Which of the following drugs may show plasmid-mediated resistance?
Options- A. Nalidixic acid
- B. Ampicillin
- C. Rifampicin
- D. Methicillin Discuss
Correct Answer: Ampicillin
- 6. Vancomycin inhibits peptidoglycan synthesis by binding
Options- A. D-alanyl - D-alanine
- B. alanine racemase
- C. D-alanyl - D-alanine synthetase
- D. amidase Discuss
Correct Answer: D-alanyl - D-alanine
- 7. The penicillin resistant to ?-lactamases is
Options- A. carbenicillin
- B. closacillin
- C. penicillin-G
- D. ampicillin Discuss
Correct Answer: closacillin
- 8. Which of the following methods would be most appropriate for sterilizing an antibiotic solution?
Options- A. Dry heat sterilization
- B. Microfiltration
- C. Autoclaving
- D. Desiccation Discuss
Correct Answer: Microfiltration
- 9. Who developed the concept of specific toxicity?
Options- A. Pasteur
- B. Fleming
- C. Watson
- D. Ehrlich Discuss
Correct Answer: Ehrlich
- 10. Bacterial cells susceptible to penicillium can be protected from destruction if the medium in which they are exposed is of
Options- A. high osmotic pressure
- B. low osmotic pressure
- C. moderate osmotic pressure
- D. high surface tension Discuss
Correct Answer: high osmotic pressure
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