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Antimicrobial Chemotherapeutic Agents problems

  • 1. Which is not an amino acid and peptide antibiotic?

  • Options
  • A. Penicillin
  • B. Actinomycin
  • C. Bacitracin
  • D. Tetranactin
  • Discuss
  • 2. Both penicillin and fluoroquinolones

  • Options
  • A. bind to and inactivate a bacterial protein
  • B. inhibit the cross-linking of peptidoglycan
  • C. are inactivated by ?-lactamase
  • D. must be transported into the cytoplasm in order to act
  • Discuss
  • 3. Which of the following protein synthesis mechanisms may be affected by particular drugs?

  • Options
  • A. Peptide bond formation
  • B. mRNA translocation
  • C. Aminoacyl-tRNA binding
  • D. All of these
  • Discuss
  • 4. Which of the following may cause resistance to penicillin?

  • Options
  • A. Impermeability of cell envelope
  • B. Production of ?-lactamases by bacteria
  • C. Alteration or lack of penicillin-binding proteins
  • D. All of the above
  • Discuss
  • 5. Fluoroquinolones are antibiotics which inhibit

  • Options
  • A. DNA polymerase
  • B. RNA polymerase
  • C. DNA gyrase
  • D. Cross-linking of peptidoglycan
  • Discuss
  • 6. Which of the following is a drug that interferes with the process of DNA production in the virus that causes genital herpes?

  • Options
  • A. Erythromycin
  • B. Vancomycin
  • C. Amantadine
  • D. Acyclovir
  • Discuss
  • 7. The antibiotics which affords a broad spectrum of antimicrobial coverage against aerobic and anaerobic bacteria, rickettsiae, chlamydiae, and mycoplasmas is

  • Options
  • A. gentamicin
  • B. tetracycline
  • C. metronidazole
  • D. vancomycin
  • Discuss
  • 8. When using alcohol as an antiseptic, which concentration is considered most effective?

  • Options
  • A. 95%
  • B. 50%
  • C. 70%
  • D. 25%
  • Discuss
  • 9. The compound(s) which act(s) as metabolic antagonist is/are

  • Options
  • A. trimethoprim
  • B. sulphonamides
  • C. both (a) and (b)
  • D. none of these
  • Discuss
  • 10. The scientist who first discovered the substance penicillin was

  • Options
  • A. Joseph Lister
  • B. Alexander Fleming
  • C. Paul Ehrlich
  • D. none of these
  • Discuss

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