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CuriousTab

Immune System problems


  • 1. Natural killer cells are involved in

  • Options
  • A. tumour rejection
  • B. allograft rejection
  • C. non-specific killing of virus transformed target cells
  • D. all of these
  • Discuss
  • 2. Which of the following is correct for isoantigens?

  • Options
  • A. They are antigens found in all members of different species
  • B. They are antigens found in some members of a species
  • C. They are antigens found in all members of a species
  • D. They are antigens found in some members of different species
  • Discuss
  • 3. Numerous antibodies can be prepared, against one antigen, each binds to unique epitopes. How is this antibody diversity generated?

  • Options
  • A. By rearrangements of the DNA encoding the variable regions of the heavy and light chains
  • B. By the combination of different heavy and light chains that form the antigen binding site
  • C. Antibody proteins can physically change their shape to bind different epitopes
  • D. Both (a) and (b)
  • Discuss
  • 4. Which of the following proteins would not need localization signal?

  • Options
  • A. A nuclear protein
  • B. A cytosolic protein
  • C. A protein bound to the endoplasmic reticulum (ER) membrane
  • D. A cell surface protein
  • Discuss
  • 5. Which of the following(s) is/are the determinants of antigenicity?

  • Options
  • A. Chemical nature
  • B. Size of the antigen
  • C. Foreignness
  • D. All of these
  • Discuss
  • 6. Major Histo Compatibility Complex (MHC) is a collection of genes arrayed on

  • Options
  • A. chromosome 21 in man, chromosome 6 in mice
  • B. chromosome 6 in man, chromosone 21 in mice
  • C. chromosome 17in man, chromosome 6 in mice
  • D. chromosome 6 in man, chromosome 17 in mice
  • Discuss
  • 7. Macrophages are professional antigen- presenting cells. The protein molecule through which they present antigen in human is

  • Options
  • A. actin
  • B. interleukin
  • C. HLA
  • D. CD8
  • Discuss
  • 8. Polymorphonuclear leukocytes (or PMNs)

  • Options
  • A. can be attracted to the site of an infection following activation of complement
  • B. are derived from bone marrow stem cells
  • C. are a type of phagocyte that can engulf and kill bacteria
  • D. all of the above
  • Discuss
  • 9. Which of the following expresses CD3 surface antigen?

  • Options
  • A. Granulocytes
  • B. T cells
  • C. Monocytes
  • D. B cells
  • Discuss
  • 10. CD8 surface antigen is present in

  • Options
  • A. cytotoxic T cells
  • B. suppresssor T cells
  • C. both (a) and (b)
  • D. none of these
  • Discuss

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