Translation and Regulation problems
- 1. Which of the following defines an open reading frame (ORF)?
Options- A. A sequence of genome in bacteriophage
- B. The sequence of a complete genome
- C. A plasmid vector used in genome sequencing
- D. A possible gene predicted by DNA sequencing Discuss
Correct Answer: A possible gene predicted by DNA sequencing
- 2. The final step of gene expression is protein synthesis, which is also known as
Options- A. replication
- B. translation
- C. transcription
- D. none of these Discuss
Correct Answer: translation
- 3. Site in the ribosome from which the tRNA donates amino acids to the growing polypeptide chain is
Options- A. P site
- B. O site
- C. T site
- D. A site Discuss
Correct Answer: P site
- 4. During amino acid activation a(n)
Options- A. amino acid is bound to tRNA
- B. amino acid is bound to mRNA
- C. methyl group is attached to rRNA
- D. methyl group is attached to an amino acid Discuss
Correct Answer: amino acid is bound to tRNA
- 5. Which of the following molecule catalyzes the transpeptidation reaction?
Options- A. RNA polymerase
- B. Peptidyl transferase
- C. DNA ligase
- D. DNA polymerase Discuss
Correct Answer: Peptidyl transferase
- 6. The Shine-Dalgarno sequence is
Options- A. trailer sequence
- B. a stop codon
- C. the reading frame of a gene
- D. a short sequence that acts as a ribosomal binding site Discuss
Correct Answer: a short sequence that acts as a ribosomal binding site
- 7. The nonsense codon(s) is/are
Options- A. UAG
- B. UAA
- C. UGA
- D. all of these Discuss
Correct Answer: all of these
- 8. Which phage always carries a small piece of E.coli genome?
Options- A. Lambda
- B. Mu
- C. T4
- D. T3 Discuss
Correct Answer: Mu
- 9. The role of molecular chaperones is to
Options- A. facilitate binding of ribosomes to mRNA
- B. degrade newly synthesized polypeptides that contain inaccurate sequences
- C. facilitate binding of RNA polymerase to DNA
- D. aid a newly synthesized polypeptide in folding to its proper shape Discuss
Correct Answer: aid a newly synthesized polypeptide in folding to its proper shape
- 10. Which of the following is a nontranslated sequence located between the transcription and the translation start site?
Options- A. Ending frame
- B. Leader sequence
- C. Trailer sequence
- D. Reading frame Discuss
Correct Answer: Leader sequence
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