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  • Question
  • A deficiency of the enzyme Hypoxanthine Guanine phosphoribosyl transferase (HGPRT) may cause


  • Options
  • A. Gaucher's disease
  • B. Ehlers-Danlos syndrome
  • C. Lesch- Nyhan syndrome
  • D. Kleinefelter's syndrome

  • Correct Answer
  • Lesch- Nyhan syndrome 


  • Disorders problems


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    • 1. Which of the protein is involved in Alzheimer's disease?

    • Options
    • A. A4
    • B. Amylin
    • C. Fibrin
    • D. Alzhemin
    • Discuss
    • 2. Which of the modification in hemoglobin is the cause of sickle cell anemia?

    • Options
    • A. A mutation in the beta chain
    • B. A deletion in the beta chain
    • C. Replacement of the B chain by D chain
    • D. None of the above
    • Discuss
    • 3. Biochips are made up of

    • Options
    • A. semi-conducting molecules inserted into the protein frame work
    • B. conducting molecules inserted into the protein frame work
    • C. non-conducting molecules inserted into the protein frame work
    • D. any of the above
    • Discuss
    • 4. To qualify as a micro array the analytical device must be

    • Options
    • A. ordered
    • B. microscopic
    • C. planer and specific
    • D. all of these
    • Discuss
    • 5. A micro array is an ordered array of microscopic elements on a planer substrate that allows the specific binding of

    • Options
    • A. gene or gene products
    • B. whole genome
    • C. both (a) and (b)
    • D. none of these
    • Discuss
    • 6. The disorder in which of the following may cause "Ehlers-Danlos Syndrome"?

    • Options
    • A. Dlashin protein
    • B. Collagen protein
    • C. Fibrin protein
    • D. Globulin protein
    • Discuss
    • 7. Methotrexate is toxic to human cells because it inhibits

    • Options
    • A. formation of CTP from UTP
    • B. reduction of H2 folate to H4 folate
    • C. synthesis of PRPP
    • D. none of the above
    • Discuss
    • 8. During sickle cell anemia which of the following takes place?

    • Options
    • A. Glutamine change to valine
    • B. Valine change to glutamine
    • C. Aspartic acid change to glutamic acid
    • D. Glutamic acid change to aspartic acid
    • Discuss
    • 9. What is the defective enzyme in the glycogen storage Von Gierke's disease?

    • Options
    • A. Phosphorylase
    • B. Phosphofructokinase
    • C. Glucose-6-phosphatase
    • D. None of the above
    • Discuss
    • 10. If the RBC of human were kept in 0.9% NaCl solution, what sort of change will occur to RBC?

    • Options
    • A. Cell will Burst
    • B. Cell will shrink
    • C. No change to RBC
    • D. RBC will destroy
    • Discuss


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