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Home Microbiology Antimicrobial Chemotherapeutic Agents Comments

  • Question
  • Both penicillin and fluoroquinolones


  • Options
  • A. bind to and inactivate a bacterial protein
  • B. inhibit the cross-linking of peptidoglycan
  • C. are inactivated by ?-lactamase
  • D. must be transported into the cytoplasm in order to act

  • Correct Answer
  • bind to and inactivate a bacterial protein 


  • Antimicrobial Chemotherapeutic Agents problems


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    • 1. Which is not an amino acid and peptide antibiotic?

    • Options
    • A. Penicillin
    • B. Actinomycin
    • C. Bacitracin
    • D. Tetranactin
    • Discuss
    • 2. Novobiocin can be used against

    • Options
    • A. gram +ve Staphylococci
    • B. gram -ve Meningococci & Gonococci
    • C. Haemophilus
    • D. all of these
    • Discuss
    • 3. Which of the following tests is used to determine the minimal lethal concentration?

    • Options
    • A. Broth dilution test
    • B. Agar dilution test
    • C. Dilution susceptibility tests
    • D. All of these
    • Discuss
    • 4. The antibiotics not having good activity against Enterobacteriaceae is

    • Options
    • A. clindamycin
    • B. cefoxitin
    • C. trimethoprim-sulphamethoxazole
    • D. ciprofloxacin
    • Discuss
    • 5. Which of the following is not ?-lactamase-resistant penicillin?

    • Options
    • A. Oxacillin
    • B. Nafcillin
    • C. Carbenicillin
    • D. Methicillin
    • Discuss
    • 6. Which of the following protein synthesis mechanisms may be affected by particular drugs?

    • Options
    • A. Peptide bond formation
    • B. mRNA translocation
    • C. Aminoacyl-tRNA binding
    • D. All of these
    • Discuss
    • 7. Which of the following may cause resistance to penicillin?

    • Options
    • A. Impermeability of cell envelope
    • B. Production of ?-lactamases by bacteria
    • C. Alteration or lack of penicillin-binding proteins
    • D. All of the above
    • Discuss
    • 8. Fluoroquinolones are antibiotics which inhibit

    • Options
    • A. DNA polymerase
    • B. RNA polymerase
    • C. DNA gyrase
    • D. Cross-linking of peptidoglycan
    • Discuss
    • 9. Which of the following is a drug that interferes with the process of DNA production in the virus that causes genital herpes?

    • Options
    • A. Erythromycin
    • B. Vancomycin
    • C. Amantadine
    • D. Acyclovir
    • Discuss
    • 10. The antibiotics which affords a broad spectrum of antimicrobial coverage against aerobic and anaerobic bacteria, rickettsiae, chlamydiae, and mycoplasmas is

    • Options
    • A. gentamicin
    • B. tetracycline
    • C. metronidazole
    • D. vancomycin
    • Discuss


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