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Home Microbiology Antimicrobial Chemotherapeutic Agents Comments

  • Question
  • The mode of action of polymyxin is to


  • Options
  • A. inhibit protein synthesis
  • B. inhibit DNA synthesis
  • C. injury to the plasma membrane
  • D. inhibit folic acid synthesis

  • Correct Answer
  • injury to the plasma membrane 


  • Antimicrobial Chemotherapeutic Agents problems


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    • 1. By which of the following means antifungal chemotherapeutic agents may affect fungi?

    • Options
    • A. Interfere with nuclear division by preventing the aggregation of microtubules needed for mitosis
    • B. Interfere with normal nucleic acid synthesis
    • C. Interfere with ergosterol biosynthesis and thus alter the structure of the cytoplasmic membrane as well as the function of several membrane-bound enzymes like those involved in nutrient transport and chitin synthesis
    • D. all of these
    • Discuss
    • 2. The larger the __________ , the better the chemotherapeutic agent.

    • Options
    • A. therapeutic index
    • B. therapeutic dose
    • C. selective toxicity
    • D. spectrum
    • Discuss
    • 3. Cycloserine inhibits

    • Options
    • A. alanine racemase
    • B. D-alanyl - D-alanine synthetase
    • C. Both (a) and (b)
    • D. amidase
    • Discuss
    • 4. Which of the following is not a semi synthetic chemotherapeutic agent?

    • Options
    • A. Ampicillin
    • B. Carbenicillin
    • C. Penicillin
    • D. Sulfonamide
    • Discuss
    • 5. Which of the following is not an aminoglycoside antibiotic?

    • Options
    • A. Streptomycin
    • B. Neomycin
    • C. Kanamycin
    • D. Cephalosporin
    • Discuss
    • 6. Which of the following is not an example of potent antitumer agents?

    • Options
    • A. Anthramycin
    • B. Sibromycin
    • C. Neothramycin
    • D. Erythromycin
    • Discuss
    • 7. The most selective antibiotics are those that interfere with the synthesis of

    • Options
    • A. bacterial DNA
    • B. bacterial RNA
    • C. bacterial cell walls
    • D. bacterial plasma membrane
    • Discuss
    • 8. A parenteral route of drug administration refers to

    • Options
    • A. oral
    • B. nonoral
    • C. intravenously
    • D. intramuscularly
    • Discuss
    • 9. With which of the following aminoglycosides interfere?

    • Options
    • A. Protein synthesis
    • B. DNA function
    • C. Cell wall synthesis
    • D. Cell membrane function
    • Discuss
    • 10. More promising chemotherapeutic agents for treating viral diseases is

    • Options
    • A. leukocytic interferon
    • B. fibroblast interferon
    • C. interferon
    • D. nystatin
    • Discuss


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