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Home ‣ Microbiology ‣ DNA Sequencing, Mutation and Repair Comments
- Question
Changes in which of the following characterizes mutations?
Options- A. Phenotype
- B. Genotype
- C. Both (a) and (b)
- D. None of these
- Correct Answer
- Both (a) and (b)
- 1. Which of these mechanisms for thymine dimers repair lead to mutations?
Options- A. Excision repair
- B. Photoreactivation
- C. SOS repair
- D. Never leads to mutation Discuss
- 2. Which of the following mutations arise without exposure to external agents?
Options- A. Spontaneous mutations
- B. Analogous mutations
- C. Induced mutations
- D. None of these Discuss
- 3. Differentiation of four different bases in automated sequencing systems is that each base has
Options- A. different radioactive tag
- B. cytosine at start
- C. unique antibody bound to it
- D. distinctive fluorescent tag Discuss
- 4. Genetic variations are
Options- A. temporary
- B. influenced by the environment
- C. stable
- D. not heritable Discuss
- 5. Due to which of the following DNA repair mechanisms, one is able to distinguish newly synthesized DNA strands from older one?
Options- A. New strands do not contain cytosine bases
- B. New strands are lower in molecular size
- C. Old strands are methylated while new strands are not
- D. New strands are methylated while old strands are not Discuss
- 6. The whole-genome shotgun sequencing approach depends primarily on
Options- A. rapidly sequencing thousands of small randomly cloned fragments
- B. methodical sequencing a few large cloned fragments of DNA
- C. sequencing the bacterial chromosome while it is still intact
- D. all of the above Discuss
- 7. A nonsense mutation introduced into the DNA sequence of a gene may
Options- A. cause premature termination of the mRNA
- B. shorten the length of the protein encoded by the gene
- C. have no effect on the transcript or protein made
- D. cause a shift in reading frame Discuss
- 8. Which of the following(s) is/are steps in excision repair mechanisms?
Options- A. Excision
- B. Incision
- C. Ligation
- D. All of these Discuss
- 9. A mutagen is defined as
Options- A. an enzyme that repairs mutations
- B. a chemical or physical agent that induces mutations
- C. an inhibitor of gene modification
- D. a molecule which stabilizes DNA thus prevents mutations from occurring Discuss
- 10. Which of the following mutation affects only a single nucleotide?
Options- A. Aerial mutation
- B. Site mutation
- C. Point mutation
- D. Regional mutation Discuss
DNA Sequencing, Mutation and Repair problems
Search Results
Correct Answer: SOS repair
Correct Answer: Spontaneous mutations
Correct Answer: distinctive fluorescent tag
Correct Answer: stable
Correct Answer: Old strands are methylated while new strands are not
Correct Answer: rapidly sequencing thousands of small randomly cloned fragments
Correct Answer: shorten the length of the protein encoded by the gene
Correct Answer: All of these
Correct Answer: a chemical or physical agent that induces mutations
Correct Answer: Point mutation
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