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Home ‣ Microbiology ‣ DNA Sequencing, Mutation and Repair Comments
- Question
Differentiation of four different bases in automated sequencing systems is that each base has
Options- A. different radioactive tag
- B. cytosine at start
- C. unique antibody bound to it
- D. distinctive fluorescent tag
- Correct Answer
- distinctive fluorescent tag
- 1. Genetic variations are
Options- A. temporary
- B. influenced by the environment
- C. stable
- D. not heritable Discuss
- 2. Due to which of the following DNA repair mechanisms, one is able to distinguish newly synthesized DNA strands from older one?
Options- A. New strands do not contain cytosine bases
- B. New strands are lower in molecular size
- C. Old strands are methylated while new strands are not
- D. New strands are methylated while old strands are not Discuss
- 3. The mutation which will not affect the length of a protein is,
Options- A. nonsense mutation
- B. missense mutation
- C. frameshift mutation
- D. all of these Discuss
- 4. The DNA sequences of rRNA genes can be used to
Options- A. assess relatedness of eukaryotes but not prokaryotes
- B. obtain a tentative identification of a new microorganism
- C. predict the pulsed field gel pattern of a microorganism
- D. predict whether a bacteria will be gram-positive or gram-negative Discuss
- 5. What was the first eukaryotic chromosome to be sequenced?
Options- A. Yeast chromosome III
- B. Yeast chromosome XI
- C. Arabidopsis chromosome IV
- D. None of these Discuss
- 6. Which of the following mutations arise without exposure to external agents?
Options- A. Spontaneous mutations
- B. Analogous mutations
- C. Induced mutations
- D. None of these Discuss
- 7. Which of these mechanisms for thymine dimers repair lead to mutations?
Options- A. Excision repair
- B. Photoreactivation
- C. SOS repair
- D. Never leads to mutation Discuss
- 8. Changes in which of the following characterizes mutations?
Options- A. Phenotype
- B. Genotype
- C. Both (a) and (b)
- D. None of these Discuss
- 9. The whole-genome shotgun sequencing approach depends primarily on
Options- A. rapidly sequencing thousands of small randomly cloned fragments
- B. methodical sequencing a few large cloned fragments of DNA
- C. sequencing the bacterial chromosome while it is still intact
- D. all of the above Discuss
- 10. A nonsense mutation introduced into the DNA sequence of a gene may
Options- A. cause premature termination of the mRNA
- B. shorten the length of the protein encoded by the gene
- C. have no effect on the transcript or protein made
- D. cause a shift in reading frame Discuss
DNA Sequencing, Mutation and Repair problems
Search Results
Correct Answer: stable
Correct Answer: Old strands are methylated while new strands are not
Correct Answer: missense mutation
Correct Answer: obtain a tentative identification of a new microorganism
Correct Answer: Yeast chromosome III
Correct Answer: Spontaneous mutations
Correct Answer: SOS repair
Correct Answer: Both (a) and (b)
Correct Answer: rapidly sequencing thousands of small randomly cloned fragments
Correct Answer: shorten the length of the protein encoded by the gene
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