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Home ‣ Microbiology ‣ DNA Sequencing, Mutation and Repair Comments
- Question
What was the first eukaryotic chromosome to be sequenced?
Options- A. Yeast chromosome III
- B. Yeast chromosome XI
- C. Arabidopsis chromosome IV
- D. None of these
- Correct Answer
- Yeast chromosome III
- 1. Which of the following bacterial genome was sequenced first?
Options- A. E. coli
- B. S. pneumoniae
- C. H. influenzae
- D. S. thermophilus Discuss
- 2. Frame shift mutation may occur as a result of
Options- A. formation of a thymine-dimer
- B. deamination of cytosine to uracil
- C. conversion of guanine to xanthine
- D. none of the above Discuss
- 3. The promoter on an expression vector used to overproduce proteins in bacteria is
Options- A. a bacterial promoter
- B. expressed both in bacteria and mammalian cells
- C. not a regulated promoter
- D. the natural promoter of the gene being cloned Discuss
- 4. A nonsense mutation may result into
Options- A. an abnormal elongation of a polypeptide
- B. a large deletion within the reading frame of a gene
- C. a premature termination of the synthesis of a polypeptide
- D. modification of mRNA Discuss
- 5. Thymine dimers are directly repaired with the help of visible light by process known as
Options- A. phosphorylation
- B. excision repair
- C. photosynthesis
- D. photoreactivation Discuss
- 6. The DNA sequences of rRNA genes can be used to
Options- A. assess relatedness of eukaryotes but not prokaryotes
- B. obtain a tentative identification of a new microorganism
- C. predict the pulsed field gel pattern of a microorganism
- D. predict whether a bacteria will be gram-positive or gram-negative Discuss
- 7. The mutation which will not affect the length of a protein is,
Options- A. nonsense mutation
- B. missense mutation
- C. frameshift mutation
- D. all of these Discuss
- 8. Due to which of the following DNA repair mechanisms, one is able to distinguish newly synthesized DNA strands from older one?
Options- A. New strands do not contain cytosine bases
- B. New strands are lower in molecular size
- C. Old strands are methylated while new strands are not
- D. New strands are methylated while old strands are not Discuss
- 9. Genetic variations are
Options- A. temporary
- B. influenced by the environment
- C. stable
- D. not heritable Discuss
- 10. Differentiation of four different bases in automated sequencing systems is that each base has
Options- A. different radioactive tag
- B. cytosine at start
- C. unique antibody bound to it
- D. distinctive fluorescent tag Discuss
DNA Sequencing, Mutation and Repair problems
Search Results
Correct Answer: H. influenzae
Correct Answer: none of the above
Correct Answer: a bacterial promoter
Correct Answer: a premature termination of the synthesis of a polypeptide
Correct Answer: photoreactivation
Correct Answer: obtain a tentative identification of a new microorganism
Correct Answer: missense mutation
Correct Answer: Old strands are methylated while new strands are not
Correct Answer: stable
Correct Answer: distinctive fluorescent tag
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