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  • Question
  • Which of the following(s) is/are the determinants of antigenicity?


  • Options
  • A. Chemical nature
  • B. Size of the antigen
  • C. Foreignness
  • D. All of these

  • Correct Answer
  • All of these 


  • Immune System problems


    Search Results


    • 1. Which of the following proteins would not need localization signal?

    • Options
    • A. A nuclear protein
    • B. A cytosolic protein
    • C. A protein bound to the endoplasmic reticulum (ER) membrane
    • D. A cell surface protein
    • Discuss
    • 2. Numerous antibodies can be prepared, against one antigen, each binds to unique epitopes. How is this antibody diversity generated?

    • Options
    • A. By rearrangements of the DNA encoding the variable regions of the heavy and light chains
    • B. By the combination of different heavy and light chains that form the antigen binding site
    • C. Antibody proteins can physically change their shape to bind different epitopes
    • D. Both (a) and (b)
    • Discuss
    • 3. Which of the following is correct for isoantigens?

    • Options
    • A. They are antigens found in all members of different species
    • B. They are antigens found in some members of a species
    • C. They are antigens found in all members of a species
    • D. They are antigens found in some members of different species
    • Discuss
    • 4. Natural killer cells are involved in

    • Options
    • A. tumour rejection
    • B. allograft rejection
    • C. non-specific killing of virus transformed target cells
    • D. all of these
    • Discuss
    • 5. What information can be generated by interrupted mating experiments?

    • Options
    • A. Levels of DNA homology
    • B. Bacterial genome maps
    • C. DNA nucleotide sequences
    • D. Proteomics of the bacteria
    • Discuss
    • 6. Major Histo Compatibility Complex (MHC) is a collection of genes arrayed on

    • Options
    • A. chromosome 21 in man, chromosome 6 in mice
    • B. chromosome 6 in man, chromosone 21 in mice
    • C. chromosome 17in man, chromosome 6 in mice
    • D. chromosome 6 in man, chromosome 17 in mice
    • Discuss
    • 7. Macrophages are professional antigen- presenting cells. The protein molecule through which they present antigen in human is

    • Options
    • A. actin
    • B. interleukin
    • C. HLA
    • D. CD8
    • Discuss
    • 8. Polymorphonuclear leukocytes (or PMNs)

    • Options
    • A. can be attracted to the site of an infection following activation of complement
    • B. are derived from bone marrow stem cells
    • C. are a type of phagocyte that can engulf and kill bacteria
    • D. all of the above
    • Discuss
    • 9. Which of the following expresses CD3 surface antigen?

    • Options
    • A. Granulocytes
    • B. T cells
    • C. Monocytes
    • D. B cells
    • Discuss
    • 10. CD8 surface antigen is present in

    • Options
    • A. cytotoxic T cells
    • B. suppresssor T cells
    • C. both (a) and (b)
    • D. none of these
    • Discuss


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