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Home Microbiology Translation and Regulation Comments

  • Question
  • What was the first bacterial genome to be sequenced and made public?


  • Options
  • A. Bacillus subtilis
  • B. Escherichia coli
  • C. Haemophilus influenzae
  • D. No bacterial genome has been sequenced yet

  • Correct Answer
  • Haemophilus influenzae 


  • Translation and Regulation problems


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    • 1. A quorum sensing system

    • Options
    • A. detects a signal from the external environment
    • B. senses a compound produced by the bacterium itself
    • C. consists of a sensor component that phosphorylates a regulatory protein
    • D. controls the activity of ribosomes directly
    • Discuss
    • 2. Which of the following is a nontranslated sequence located between the transcription and the translation start site?

    • Options
    • A. Ending frame
    • B. Leader sequence
    • C. Trailer sequence
    • D. Reading frame
    • Discuss
    • 3. The role of molecular chaperones is to

    • Options
    • A. facilitate binding of ribosomes to mRNA
    • B. degrade newly synthesized polypeptides that contain inaccurate sequences
    • C. facilitate binding of RNA polymerase to DNA
    • D. aid a newly synthesized polypeptide in folding to its proper shape
    • Discuss
    • 4. Which phage always carries a small piece of E.coli genome?

    • Options
    • A. Lambda
    • B. Mu
    • C. T4
    • D. T3
    • Discuss
    • 5. The nonsense codon(s) is/are

    • Options
    • A. UAG
    • B. UAA
    • C. UGA
    • D. all of these
    • Discuss
    • 6. Which of the following three codons translate as serine (Ser)?

    • Options
    • A. AGU
    • B. CGA
    • C. CAU
    • D. AUG
    • Discuss
    • 7. Which of the termination codon is called amber?

    • Options
    • A. UAA
    • B. UAG
    • C. UGA
    • D. AUG
    • Discuss
    • 8. What are the Svedberg values for the subunits of the 70S ribosomes of E. colli?

    • Options
    • A. 40S and 30S
    • B. 50S and 20S
    • C. 50S and 30S
    • D. 40S and 20S
    • Discuss
    • 9. The development of global regulatory systems in prokaryotes

    • Options
    • A. determines the exact location of the cell on the globe
    • B. aids in DNA replication
    • C. determines the exact location of the replication site
    • D. regulates many genes under varying environmental conditions
    • Discuss
    • 10. Which of the following statement is correct?

    • Options
    • A. The size and sequence of introns can be deduced from the cDNA sequence
    • B. Restriction endonuclease can cleave ss and dsDNA both
    • C. Restriction fragment length polymorphism (RFLP) is usually formed in coding sequence of a gene
    • D. Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide
    • Discuss


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