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Home Microbiology DNA Replication Comments

  • Question
  • DNA gyrase is inhibited by


  • Options
  • A. tetracycline
  • B. nalidixic acid
  • C. both (a) and (b)
  • D. cephalosporin

  • Correct Answer
  • nalidixic acid 


  • DNA Replication problems


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    • 1. Which of the following statements on replication in E.coli is correct?

    • Options
    • A. It occurs in a unidirectional manner
    • B. It occurs in bidirectional manner
    • C. Always uses T7 DNA polymerase when infected by T7 phage
    • D. Occurs only when ? phase has infected E. coli
    • Discuss
    • 2. The synthesis of DNA by DNA polymerase occurs in the

    • Options
    • A. 3' to 5' direction
    • B. 5' to 5' direction
    • C. 5' to 3' direction
    • D. 3' to 3' direction
    • Discuss
    • 3. DNA replication rates in prokaryotes are approximately of the order of

    • Options
    • A. 10 bases per second
    • B. 1,00 bases per second
    • C. 1,000 bases per second
    • D. 10,000 bases per second
    • Discuss
    • 4. Which of the following possesses both 5'-3' and 3'-5' exonuclease activity?

    • Options
    • A. Kornberg enzyme
    • B. DNA polymerase III
    • C. Taq DNA polymerase
    • D. None of these
    • Discuss
    • 5. During DNA replication in prokaryotes, synthesis begins on the circular chromosome

    • Options
    • A. always at the same place
    • B. at any stretch of DNA that is high in AT pairs
    • C. randomly on the chromosome
    • D. at the promoter
    • Discuss
    • 6. Which of the following repairs nicked DNA by forming a phosphodiester bond between adjacent nucleotides?

    • Options
    • A. Helicase
    • B. DNA gyrase
    • C. Topoisomerases
    • D. DNA ligase
    • Discuss
    • 7. In E.coli, which enzyme synthesizes the RNA primer for Okazaki fragments?

    • Options
    • A. DnaA
    • B. DnaC
    • C. DnaG
    • D. all of these
    • Discuss
    • 8. Both strands of DNA serve as templates concurrently in

    • Options
    • A. replication
    • B. excision repair
    • C. mismatch repair
    • D. none of these
    • Discuss
    • 9. Which of the following lacks 3'-5' exonuclease activity?

    • Options
    • A. Short fragment of DNA polymerase I
    • B. Taq DNA polymerase
    • C. T4 DNA ligase
    • D. All of the above
    • Discuss
    • 10. The interaction between the mRNA and tRNA determined the position of amino acid in a polypeptide sequence. This is called the

    • Options
    • A. stagerivity
    • B. Wobble hypothesis
    • C. promiscuity
    • D. adaptor hypothesis
    • Discuss


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