Human Genetics—RP13 Gene on Chromosome 17 The RP13 gene located on chromosome 17 encodes a protein primarily:

Introduction / Context:
Retinitis pigmentosa (RP) comprises a group of inherited retinal degenerations. Loci are often designated RP followed by a number (e.g., RP13), and map to specific chromosomal regions. Genes at these loci typically encode proteins required for retinal structure or phototransduction pathways, directly affecting eye development and function.

Given Data / Assumptions:

• RP locus numbering reflects discovery order and mapping.
• Chromosome 17 contains multiple genes implicated in ocular biology.
• RP-associated genes affect photoreceptors or retinal pigment epithelium.

Concept / Approach:
Interpret the RP nomenclature: it refers to retinitis pigmentosa, a disorder involving retinal degeneration. Therefore, the encoded proteins are tied to eye development or retinal maintenance rather than generalized transporters, keratins, personality determinants, or coagulation factors.

Step-by-Step Solution:

Verification / Alternative check:
Genetic databases and ophthalmic literature align RP loci with ocular phenotypes, supporting the eye-development association.

Why Other Options Are Wrong:

• Glucose transport and coagulation: unrelated to RP loci designation.
• Hair/nail structural proteins (keratins): different tissue specialization.
• “Personality traits”: not a recognized single-gene protein effect.

Common Pitfalls:
Misreading RP as “ribosomal protein” rather than retinitis pigmentosa; overinterpreting chromosome location without phenotype context.

Final Answer:
Involved in eye development