Viral envelopes: Which lipid class predominates in the membranes that form the viral envelope derived from host cells?

Difficulty: Easy

Correct Answer: phospholipids

Explanation:


Introduction / Context:
Enveloped viruses bud through host membranes, acquiring a lipid bilayer. Knowing its composition helps explain sensitivity to detergents, desiccation, and disinfectants.



Given Data / Assumptions:

  • Viral envelopes are derived from host plasma membrane or internal membranes.
  • Typical eukaryotic membranes are composed mainly of phospholipids and cholesterol, with smaller fractions of glycolipids.
  • Neutral fats (triacylglycerols) are storage lipids, not main bilayer components.



Concept / Approach:
The bilayer’s structural backbone is phospholipids, which form amphipathic sheets. Cholesterol modulates fluidity but is not listed among options. Therefore, the predominant lipid class is phospholipids.



Step-by-Step Solution:
Identify the source of the envelope: host membrane. Recall membrane composition: mostly phospholipids with cholesterol. Exclude storage and minor lipid classes. Choose “phospholipids”.



Verification / Alternative check:
Basic cell biology consistently places phospholipids as the principal bilayer constituents across cell and viral envelopes.



Why Other Options Are Wrong:

  • Glycolipids: Present but minor compared with phospholipids.
  • Neutral fat: Not a bilayer structural lipid.
  • All of these: Overstates contributions of non-structural lipids.
  • Ceramides only: Too narrow; sphingolipids are not exclusive.



Common Pitfalls:
Equating storage lipids with membrane structure, or assuming all lipid classes contribute equally.



Final Answer:
phospholipids.


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