Viral cytopathic effects: Intracytoplasmic inclusion bodies may be seen in cells infected with which of the following viruses?

Introduction / Context:
In diagnostic virology, inclusion bodies are hallmark cytopathic effects that help point to viral families. Distinguishing intracytoplasmic from intranuclear inclusions guides presumptive identification on histology or cytology.

Given Data / Assumptions:

• Rabies virus produces Negri bodies (cytoplasmic).
• Vaccinia virus (a poxvirus) replicates in cytoplasm and forms cytoplasmic inclusions.
• Fowlpox virus, another poxvirus, also forms cytoplasmic inclusions.

Concept / Approach:
Poxviruses replicate in the host cell cytoplasm and typically generate prominent cytoplasmic inclusion bodies. Rabies virus likewise leads to cytoplasmic Negri bodies in neurons. Therefore, multiple listed viruses share intracytoplasmic inclusion formation.

Step-by-Step Solution:
Match each virus to typical inclusion location. Rabies: Negri bodies in cytoplasm. Vaccinia/Fowlpox: cytoplasmic inclusions due to cytoplasmic replication. Therefore, select the comprehensive choice “all of these”.

Verification / Alternative check:
Histopathology texts repeatedly cite these inclusions for quick recognition and teaching slides often feature them.

Why Other Options Are Wrong:
Single-virus answers omit other correct examples; “none” is contradicted by well-known inclusions.

Common Pitfalls:
Confusing intracytoplasmic inclusions of poxviruses with intranuclear inclusions typical of herpesviruses and adenoviruses.

Final Answer:
all of these.