R plasmids terminology: Plasmids that carry both the resistance transfer factor (RTF) and resistance (r) determinants are termed what?

Difficulty: Easy

Correct Answer: Conjugative plasmids

Explanation:


Introduction / Context:
Antibiotic resistance plasmids (R plasmids) may have two functional parts: an RTF region that mediates transfer and an r-determinant region encoding resistance genes. Terminology distinguishes whether a plasmid can self-transfer.



Given Data / Assumptions:

  • RTF provides conjugation (transfer) functions.
  • r determinants encode resistance phenotypes.
  • Presence of both implies self-transmissibility.


Concept / Approach:

If a plasmid carries both RTF and r determinants, it can transfer itself by conjugation and confer resistance to recipients. Therefore it is a conjugative plasmid. Plasmids lacking transfer functions are non-conjugative and require “helper” plasmids.



Step-by-Step Solution:

Identify functional modules: RTF (transfer) + r (resistance).Determine capability: can self-transfer via conjugation.Map to term: conjugative plasmid.Select “Conjugative plasmids.”


Verification / Alternative check:

Mating experiments show such plasmids mobilize themselves and often co-mobilize other plasmids lacking transfer regions if oriT is present.



Why Other Options Are Wrong:

“Non self-transmissible” and “non-conjugative” contradict the presence of RTF.

“None of the above” is incorrect because an established term exists.



Common Pitfalls:

Confusing conjugative R plasmids with mobilizable plasmids; the latter have oriT but need transfer functions in trans.



Final Answer:

Conjugative plasmids

More Questions from Microbial Recombination and Gene Transfer

Discussion & Comments

No comments yet. Be the first to comment!
Join Discussion